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Table S1. List of RT-PCR primers used to validate the microarray data.

Table S2. Full list of mRNAs was significant differential expression in NAc by in cocaine-conditioned mice.

Table S3. Full list of lncRNAs was significant differential expression in NAc by in cocaine-conditioned mice.

Table S4. List of sense-overlap lncRNAs was significant differential expression in NAc in cocaine-conditioned mice.

Table S5. List of antisense-overlap lncRNAs was significant differential expression in NAc in cocaine-conditioned mice.

Table S6. List of intergenic lncRNAs was significant differential expression in NAc in cocaine-conditioned mice.

Table S7. List of bidirectional lncRNAs was significant differential expression in NAc in cocaine-conditioned mice.

Table S8. List of lncRNAs form UCR database was significant differential expression in NAc in cocaine-conditioned mice.

Table S9. List of other lncRNAs was significant differential expression in NAc in cocaine-conditioned mice.

Table S10. List of the lncRNAs was predicted to act in cis to their targeted loci.

Table S11. List of the lncRNAs was predicted to act in trans to their targeted loci.

Table S12. List of the lncRNAs, which acted in cis or trans to their mRNAs, to those significantly changed in the NAc of cocaine-conditioned mice.

Table S13. LncRNAs with highly correlated expression profiles to cocaine CPP scores. Correlation co-efficients were determined by Pearson's correlation.

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