These authors contributed equally to this work.
TRPC6 inhibited NMDA receptor activities and protected neurons from ischemic excitotoxicity
Article first published online: 1 NOV 2012
© 2012 International Society for Neurochemistry
Journal of Neurochemistry
Volume 123, Issue 6, pages 1010–1018, December 2012
How to Cite
J. Neurochem. (2012) 123, 1010–1018.
- Issue published online: 4 DEC 2012
- Article first published online: 1 NOV 2012
- Accepted manuscript online: 8 OCT 2012 12:10PM EST
- Manuscript Accepted: 27 SEP 2012
- Manuscript Revised: 26 SEP 2012
- Manuscript Received: 27 JUN 2012
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Figure S1. Representative traces of the [Ca2 + ]i elevation in the neurons transfected with TRPC6 (TRPC6) or control vectors (vector) and stimulated with NMDA (300 μM).
Figure S2. Cultured neurons fired action potentials in response to NMDA in the absence of TTX (n = 6).
Figure S3. Representative images of the neurons transfected with GFP-tagged TRPC6 and the transfection rate (right).
Figure S4. Representative images of TTC-stained brain sections of sham (Sham) or ischemic rats after 0, 12, 24 h reperfusion (R0, R12 and R24).
Table S1. Blood gas analysis and rectal temperature.
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