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Figure S1. Mass spectrometry of the C-terminal tail of MOPr.

Figure S2. Inhibition of (a) CaMKII- or (b) PKC-induced phosphorylation of GST fusion proteins of MOPr with the selective CaMKII inhibitor KN93 or the selective PKC inhibitor GF109203X (each 10 μM), respectively.

Figure S3. Concentration-dependent interaction of arrestin-2 and -3 with a GST fusion protein of the C-terminus of MOPr in vitro.

Figure S4. Time-dependent interaction of arrestin-2 and -3 with a GST fusion protein of the C-terminus of MOPr in vitro.

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