• Caccamo A., Majumder S., Richardson A., Strong R. and Oddo S. (2010) Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. J. Biol. Chem. 285, 1310713120.
  • Fonte V., Kipp D. R., Yerg III J., Merin D., Forrestal M., Wagner E., Roberts C. M. and Link C. D. (2008) Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein. J. Biol. Chem. 283, 784791.
  • Harrison D. E., Strong R., Sharp Z. D. et al. (2009) Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460, 392395.
  • Li F., Calingasan N. Y., Yu F. et al. (2004) Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. J. Neurochem. 89, 13081312.
  • Lin M. T. and Beal M. F. (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787795.
  • Ma T., Hoeffer C. A., Capetillo-Zarate E., Yu F., Wong H., Lin M. T., Tampellini D., Klann E., Blitzer R. D. and Gouras G. K. (2010) Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease. PLoS ONE 5, doi:pii e12845.
  • Pierce A., Podlutskaya N., Halloran J. J., Hussong S. A., Lin P. Y., Burbank R., Strong R., Richardson A., Hart M. J. and Galvan V. (2012) Overexpression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease. J. Neurochem. Published Online doi: 10.1111/jnc.12080.
  • Spilman P., Podlutskaya N., Hart M. J., Debnath J., Gorostiza O., Bredesen D., Richardson A., Strong R. and Galvan V. (2010) Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. PLoS ONE 5, e9979.
  • Tsokas P., Grace E. A., Chan P., Ma T., Sealfon S. C., Iyengar R., Landau E. M. and Blitzer R. D. (2005) Local protein synthesis mediates a rapid increase in dendritic elongation factor 1A after induction of late long-term potentiation. J. Neurosci. 25, 58335843.
  • Westmark C. J. and Malter J. S. (2007) FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol. 5, e52.