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  • Able S. L., Fish R. L., Bye H., Booth L., Logan Y. R., Nathaniel C., Hayter P. and Katugampola S. D. (2011) Receptor localization, native tissue binding and ex vivo occupancy for centrally penetrant P2X7 antagonists in the rat. Br. J. Pharmacol. 162, 405414.
  • Adinolfi E., Callegari M. G., Ferrari D., Bolognesi C., Minelli M., Wieckowski M. R., Pinton P., Rizzuto R. and Di Virgilio F. (2005) Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. Mol. Biol. Cell 16, 32603272.
  • Adinolfi E., Cirillo M., Woltersdorf R. et al. (2010) Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor. FASEB J. 24, 33933404.
  • Alloisio S., Aiello R., Ferroni S. and Nobile M. (2006) Potentiation of native and recombinant P2X7-mediated calcium signaling by arachidonic acid in cultured cortical astrocytes and human embryonic kidney 293 cells. Mol. Pharmacol. 69, 19751983.
  • Alloisio S., Cervetto C., Passalacqua M., Barbieri F., Maura G., Nobile M. and Marcoli M. (2008) Functional evidence for presynaptic P2X7 receptors in adult rat cerebrocortical nerve terminals. FEBS Lett. 582, 39483953.
  • Alloisio S., Di Garbo A., Barbieri R., Bozzo L., Ferroni S. and Nobile M. (2010) Evidence for two conductive pathways in P2X7 receptor: differences in modulation and selectivity. J. Neurochem. 113, 796806.
  • Arbeloa J., Perez-Samartin A., Gottlieb M. and Matute C. (2012) P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia. Neurobiol. Dis. 45, 954961.
  • Atkinson L., Batten T. F., Moores T. S., Varoqui H., Erickson J. D. and Deuchars J. (2004) Differential co-localisation of the P2X7 receptor subunit with vesicular glutamate transporters VGLUT1 and VGLUT2 in rat CNS. Neuroscience 123, 761768.
  • Ballerini P., Rathbone M. P., Di Iorio P., Renzetti A., Giuliani P., D'Alimonte I., Trubiani O., Caciagli F. and Ciccarelli R. (1996) Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release. NeuroReport 7, 25332537.
  • Barbieri R., Alloisio S., Ferroni S. and Nobile M. (2008) Differential crosstalk between P2X7 and arachidonic acid in activation of mitogen-activated protein kinases. Neurochem. Int. 53, 255262.
  • Benfenati V., Caprini M., Nicchia G. P., Rossi A., Dovizio M., Cervetto C., Nobile M. and Ferroni S. (2009) Carbenoxolone inhibits volume-regulated anion conductance in cultured rat cortical astroglia. Channels (Austin) 3, 323336.
  • Bennett M. R., Farnell L. and Gibson W. G. (2009) P2X7 regenerative-loop potentiation of glutamate synaptic transmission by microglia and astrocytes. J. Theor. Biol. 261, 116.
  • Bradley H. J., Baldwin J. M., Goll G. R., Johnson B., Zou J., Sivaprasadarao A., Baldwin S. A. and Jiang L.-H. (2011) Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms. J. Biol. Chem. 286, 81768187.
  • Bruzzone R., Barbe M. T., Jakob N. J. and Monyer H. (2005) Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. J. Neurochem. 92, 10331043.
  • Burnstock G. (2007) Physiology and pathophysiology of purinergic neurotransmission. Physiol. Rev. 87, 659797.
  • Cankurtaran-Sayar S., Sayar K. and Ugur M. (2009) P2X7 receptor activates multiple selective dye permeation pathways in 264.7 and HEK-293. Mol. Pharmacol. 76, 13231332.
  • Cheewatrakoolpong B., Gilchrest H., Anthes J. C. and Greenfeder S. (2005) Identification and characterization of splice variants of the human P2X7 ATP channel. Biochem. Biophys. Res. Commun. 332, 1727.
  • Costa-Junior H. M., Sarmento Vieira F. and Coutinho-Silva R. (2011) C terminus of the P2X7 receptor: treasure hunting. Purinergic Signal. 7, 719.
  • Denlinger L. C., Fisette P. L., Sommer J. A., Watters J. J., Prabhu U., Dubyak G. R., Proctor R. A. and Bertics P. J. (2001) Cutting edge: the nucleotide receptor P2X7 contains multiple proteinand lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide. J. Immunol. 167, 18711876.
  • Deuchars S. A., Atkinson L., Brooke R. E., Musa H., Milligan C. J., Batten T. F., Buckley N. J., Parson S. H. and Deuchars J. (2001) Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems. J. Neurosci. 21, 71437152.
  • Di Virgilio F. (2007) The P2X7 receptor for extracellular ATP: is pannexin-1 the elusive large conductance pore? Cell Sci. Rev. 3, 3142.
  • Duan S. and Neary J. T. (2006) P2X7 Receptors: Properties and Relevance to CNS Function. Glia 54, 738746.
  • Duan S., Anderson C. M., Keung E. C., Chen Y., Chen Y. and Swanson R. A. (2003) P2X7 receptor mediated release of excitatory amino acids from astrocytes. J. Neurosci. 23, 13201328.
  • Ferrari D., Pizzirani C., Adinolfi E., Lemoli R. M., Curti A., Idzko M., Panther E. and Di Virgilio F. (2006) The P2X7 receptor: a key player in IL-1 processing and release. J. Immunol. 176, 38773883.
  • Fuller S. J., Stokes L., Skarratt K. K., Gu B. J. and Wiley J. S. (2009) Genetics of the P2X7 receptor and human disease. Purinergic Signal. 5, 257262.
  • Grygorowicz T., Struzyńska L., Sulkowski G., Chalimoniuk M. and Sulejczak D. (2010) Temporal expression of P2X7 purinergic receptor during the course of experimental autoimmune encephalomyelitis. Neurochem. Int. 57, 823829.
  • Grynkiewicz G., Poenie M. and Tsien R. Y. (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 34403450.
  • Guescini M., Leo G., Genedani S. et al. (2012) Microvesicles and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures. Exp. Cell Res. 318, 603613.
  • Guida P., Gavazzo P. and Marchetti C. (2008) A rapid and efficient protocol for transfecting NMDA receptor channels into mammalian cells, in Amino Acid Receptor Research (Paley B.F. and Warfield T.E., eds) pp 916. Nova Science Publishers, Hauppauge NY, USA.
  • Hamilton N., Vayro S., Kirchhoff F., Verkhratsky A., Robbins J., Gorecki D. C. and Butt A. M. (2008) Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes. Glia 56, 734749.
  • Humphreys B. D., Virginio C., Surprenant A., Rice J. and Dubyak G. R. (1998) Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. Mol. Pharmacol. 54, 2232.
  • Jiang L. H., Rassendren F., Mackenzie A., Zhang Y. H., Surprenant A. and North R. A. (2005) N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X7 receptors. Am. J. Physiol. Cell Physiol. 289, C1295C1302.
  • Leon D., Sanchez-Nogueiro J., Marın-Garcıa P. and Miras-Portugal M. T. (2008) Glutamate release and synapsin-I phosphorylation induced by P2X7 receptors activation in cerebellar granule neurons. Neurochem. Int. 52, 11481159.
  • Locovei S., Scemes E., Qiu F., Spray D. C. and Dahl G. (2007) Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett. 581, 483488.
  • Lundy P. M., Hamilton M. G., Mi L., Gong W., Vair C., Sawyer T. W. and Frew R. (2002) Stimulation of Ca2+ influx through ATP receptors on rat brain synaptosomes: identification of functional P2X7 receptor subtypes. Br. J. Pharmacol. 135, 16161626.
  • MacKenzie A., Wilson H. L., Kiss-Toth E., Dower S. K., North R. A. and Surprenant A. (2001) Rapid secretion of interleukin-1β by microvesicle shedding. Immunity 8, 825835.
  • Marcoli M., Bonfanti A., Roccatagliata P., Chiaramonte G., Ongini E., Raiteri M. and Maura G. (2004) Glutamate efflux from human cerebrocortical slices during ischemia: vesicular-like mode of glutamate release and sensitivity to A(2A) adenosine receptor blockade. Neuropharmacology 47, 884891.
  • Marcoli M., Cervetto C., Paluzzi P., Guarnieri S., Alloisio S., Thellung S., Nobile M. and Maura G. (2008) P2X7 presynaptic receptors in adult rat cerebrocortical nerve terminals: a role in ATP-induced glutamate release. J. Neurochem. 105, 23302342.
  • Marques-da-Silva C., Chaves M. M., Castro N. G., Coutinho-Silva R. and Guimaraes M. Z. P. (2011) Colchicine inhibits cationic dye uptake induced by ATP in P2X2- and P2X7 receptor-expressing cells: implications for its therapeutic action. Br. J. Pharmacol. 163, 912926.
  • Massone S., Argellati F., Passalacqua M., Armirotti A., Melone L., d'Abramo C., Marinari U. M., Domenicotti C., Pronzato M. A. and Ricciarelli R. (2007) Downregulation of myosin II-B by siRNA alters the subcellular localization of the amyloid precursor protein and increases amyloid-β deposition in N2a cells. Biochem. Biophys. Res. Commun. 362, 633638.
  • Miras-Portugal M. T., Diaz-Hernandez M., Giraldez L., Hervas C., Gomez-Villafuertes R., Sen R. P., Gualix J. and Pintor J. (2003) P2X7 receptors in rat brain: presence in synaptic terminals and granule cells. Neurochem. Res. 28, 15971605.
  • Nilius B. and Droogmans G. (2003) Amazing chloride channels: an overview. Acta Physiol. Scand. 177, 119147.
  • North R. A. (2002) Molecular physiology of P2X receptors. Physiol. Rev. 82, 10131067.
  • Pelegrin P. (2011) Many ways for P2X7 receptor pore dilatation. Br. J. Pharmacol. 163, 901906.
  • Pelegrin P. and Surprenant A. (2006) Pannexin-1 mediates large pore formation and interleukin-1b release by the ATP-gated P2X7 receptor. EMBO J. 25, 50715082.
  • Pellegatti P., Falzoni S., Pinton P., Rizzuto R. and Di Virgilio F. (2005) A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. Mol. Biol. Cell 16, 36593665.
  • Qu Y. and Dubyak G. R. (2009) P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways. Purinergic Signal. 5, 163173.
  • Rassendren F., Buell G. N., Virginio C., Collo G., North R. A. and Surprenant A. (1997) The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA. J. Biol. Chem. 272, 54825486.
  • Roger S., Gillet L., Baroja-Mazo A., Surprenant A. and Pelegrin P. (2010) C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation. J. Biol. Chem. 285, 1751417524.
  • Rossi D. J., Brady J. D. and Mohr C. (2007) Astrocyte metabolism and signaling during brain ischemia. Nat. Neurosci. 10, 13771386.
  • Shimamoto K., Lebrun B., Yasuda-Kamatani Y., Sakaitani M., Shigeri Y., Yumoto N. and Nakajima T. (1998) DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters. Mol. Pharmacol. 53, 195201.
  • Silverman W., Locovei S. and Dahl G. (2008) Probenecid, a gout remedy, inhibits pannexin 1 channels. Am. J. Physiol. Cell Physiol. 295, C761C767.
  • Smart M. L., Gu B., Panchal R. G., Wiley J., Cromer B., Williams D. A. and Petrou S. (2003) P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region. J. Biol. Chem. 278, 88538860.
  • Sperlagh B., Kofalvi A., Deuchars J., Atkinson L., Milligan C. J., Buckley N. J. and Vizi E. S. (2002) Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus. J. Neurochem. 81, 11961211.
  • Sperlagh B., Vizi E. S., Wirkner K. and Illes P. (2006) P2X7 receptors in the nervous system. Prog. Neurobiol. 78, 327346.
  • Suadicani S. O., Brosnan C. F. and Scemes E. (2006) P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J. Neurosci. 26, 13781385.
  • Sun C., Chu J., Singh S. and Salter R. D. (2010) Identification and characterization of a novel variant of the human P2X7 receptor resulting in gain of function. Purinergic Signal. 6, 3145.
  • Surprenant A., Rassendren F., Kawashima E., North R. A. and Buell G. (1996) The Cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272, 735738.
  • Thompson B. A. N., Storm M. P., Hewinson J., Hogg S., Welham M. J. and MacKenzie A. B. (2012) A novel role for P2X7 receptor signalling in the survival of mouse embryonic stem cells. Cell. Signal. 24, 770778.
  • Toki H., Namikawa K., Su Q., Kiryu-Seo S., Sato K. and Kiyama H. (1998) Enhancement of extracellular glutamate scavenge system in injured motoneurons. J. Neurochem. 71, 913919.
  • Verkhrasky A., Krishtal O. A. and Burnstock G. (2009) Purinoceptors on neuroglia. Mol. Neurobiol. 39, 190208.
  • Virginio C., MacKenzie A., Rassendren F. A., North R. A. and Surprenant A. (1999) Pore dilation of neuronal P2X receptor channels. Nat. Neurosci. 2, 315321.
  • Wilson H. L., Wilson S. A., Surprenant A. and North R. A. (2002) Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus. J. Biol. Chem. 277, 3401734023.
  • Yan Z., Li S., Liang Z., Tomic M. and Stojilkovic S. S. (2008) The P2X7 receptor channel pore dilates under physiological ion conditions. J. Gen. Physiol. 132, 563573.
  • Yan Z., Khadra A., Li S., Tomic M., Sherman A. and Stojilkovic S. S. (2010) Experimental characterization and mathematical modeling of P2X7 receptor channel gating. J. Neurosci. 30, 1421314224.
  • Ye Z. C., Oberheim N., Kettenmann H. and Ransom B. R. (2009) Pharmacological “cross-inhibition” of connexin hemichannels and swelling activated anion channels. Glia 57, 258269.