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Figure S1. Monitoring cell death in parallel of measuring BzATP-evoked [3H]d-aspartate efflux in HEK293 cells stably expressing rP2X7 receptor.

Figure S2. Surface expression of full-length rP2X7 receptor, truncated rP2X7 receptor lacking the C-tail (rP2X7tr), or P2X7 receptor with deletion of the 18-amino acid cysteine-rich motif of the C-tail (rP2X7∆ Cys-rich) on HEK293 cell membrane.

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