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  • Abdelmohsen K., Hutchison E. R., Lee E. K. et al. (2010) miR-375 inhibits differentiation of neurites by lowering HuD levels. Mol. Cell. Biol. 30, 41974210.
  • Abdolmaleky H. M., Cheng K. H., Russo A. et al. (2005) Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am. J. Med. Genet. B Neuropsychiatr. Genet. 134B, 6066.
  • Agrawal A., Tay J., Yang G. E., Agrawal S. and Gupta S. (2010) Age-associated epigenetic modifications in human DNA increase its immunogenicity. Aging (Albany NY) 2, 93100.
  • Akiba S., Mizunaga S., Kume K., Hayama M. and Sato T. (1999) Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells. J. Biol. Chem. 274, 1990619912.
  • Albrecht S., Bourdeau M., Bennett D., Mufson E. J., Bhattacharjee M. and LeBlanc A. C. (2007) Activation of caspase-6 in aging and mild cognitive impairment. Am. J. Pathol. 170, 12001209.
  • Bartrés-Faz D., Junqué C., López-Alomar A., Valveny N., Moral P., Casamayor R., Salido A., Bel C. and Clemente I. C. (2001) Neuropsychological and genetic differences between age-associated memory impairment and mild cognitive impairment entities. J. Am. Geriatr. Soc. 49, 985990.
  • Bas O., Songur A., Sahin O., Mollaoglu H., Ozen O. A., Yaman M., Eser O., Fidan H. and Yagmurca M. (2007) The protective effect of fish n-3 fatty acids on cerebral ischemia in rat hippocampus. Neurochem. Int. 50, 548554.
  • Basselin M., Villacreses N. E., Chen M., Bell J. M. and Rapoport S. I. (2007a) Chronic carbamazepine administration reduces N-methyl-D-aspartate receptor-initiated signaling via arachidonic acid in rat brain. Biol. Psychiatry 62, 934943.
  • Basselin M., Villacreses N. E., Lee H. J., Bell J. M. and Rapoport S. I. (2007b) Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation. J. Neurochem. 102, 761772.
  • Basselin M., Kim H. W., Chen M., Ma K., Rapoport S. I., Murphy R. C. and Farias S. E. (2010) Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation. J. Lipid Res. 51, 10491056.
  • Bazan N. G. (2005) Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Brain Pathol. 15, 159166.
  • Bishop N. A., Lu T. and Yankner B. A. (2010) Neural mechanisms of ageing and cognitive decline. Nature 464, 529535.
  • Blais V. and Rivest S. (2001) Inhibitory action of nitric oxide on circulating tumor necrosis factor-induced NF-kappaB activity and COX-2 transcription in the endothelium of the brain capillaries. J. Neuropathol. Exp. Neurol. 60, 893905.
  • Block M. L., Zecca L. and Hong J. S. (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 8, 5769.
  • Bollati V., Galimberti D., Pergoli L., Dalla Valle E., Barretta F., Cortini F., Scarpini E., Bertazzi P. A. and Baccarelli A. (2011) DNA methylation in repetitive elements and Alzheimer disease. Brain Behav. Immun. 25, 10781083.
  • Brinkman S. D., Pomara N., Barnett N., Block R., Domino E. F. and Gershon S. (1984) Lithium-induced increases in red blood cell choline and memory performance in Alzheimer-type dementia. Biol. Psychiatry 19, 157164.
  • Calvanese V., Lara E., Kahn A. and Fraga M. F. (2009) The role of epigenetics in aging and age-related diseases. Ageing Res. Rev. 8, 268276.
  • Chen K. L., Wang S. S., Yang Y. Y., Yuan R. Y., Chen R. M. and Hu C. J. (2009) The epigenetic effects of amyloid-beta(1–40) on global DNA and neprilysin genes in murine cerebral endothelial cells. Biochem. Biophys. Res. Commun. 378, 5761.
  • Chen K. H., Reese E. A., Kim H. W., Rapoport S. I. and Rao J. S. (2011) Disturbed neurotransmitter transporter expression in Alzheimer's disease brain. J. Alzheimers Dis. 26, 755766.
  • Dandekar D. H., Ganesh K. N. and Mitra D. (2004) HIV-1 Tat directly binds to NFkappaB enhancer sequence: role in viral and cellular gene expression. Nucleic Acids Res. 32, 12701278.
  • Dong E., Agis-Balboa R. C., Simonini M. V., Grayson D. R., Costa E. and Guidotti A. (2005) Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proc. Natl Acad. Sci. USA 102, 1257812583.
  • Dröge W. and Schipper H. M. (2007) Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 6, 361370.
  • Dwivedi Y., Rizavi H. S., Rao J. S. and Pandey G. N. (2000) Modifications in the phosphoinositide signaling pathway by adrenal glucocorticoids in rat brain: focus on phosphoinositide-specific phospholipase C and inositol 1,4,5-trisphosphate. J. Pharmacol. Exp. Ther. 295, 244254.
  • Egger G., Liang G., Aparicio A. and Jones P. A. (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429, 457463.
  • Esposito G., Giovacchini G., Liow J. S. et al. (2008) Imaging neuroinflammation in Alzheimer's disease with radiolabeled arachidonic acid and PET. J. Nucl. Med. 49, 14141421.
  • Florent S., Malaplate-Armand C., Youssef I. et al. (2006) Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers. J. Neurochem. 96, 385395.
  • Folstein M. D. M., Liu M. D. T., Peter P. D. I., Buel B. S. J., Arsenault B. S. L., Scott P. D. T. and Qiu M. D. P. D. W. (2007) The homocysteine hypothesis of depression. Am. J. Psychiatry 164, 861867.
  • Fraga M. F. and Esteller M. (2007) Epigenetics and aging: the targets and the marks. Trends Genet. 23, 413418.
  • Galimberti D., Fenoglio C. and Scarpini E. (2008) Inflammation in neurodegenerative disorders: friend or foe? Curr. Aging Sci. 1, 3041.
  • Hatanpaa K., Isaacs K. R., Shirao T., Brady D. R. and Rapoport S. I. (1999) Loss of proteins regulating synaptic plasticity in normal aging of the human brain and in Alzheimer disease. J. Neuropathol. Exp. Neurol. 58, 637643.
  • Hebert L. E., Scherr P. A., Bienias J. L., Bennett D. A. and Evans D. A. (2003) Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch. Neurol. 60, 11191122.
  • Hedden T. and Gabrieli J. D. E. (2004) Insights into the ageing mind: a view from cognitive neuroscience. Nat. Rev. Neurosci. 5, 8796.
  • Hernandez M., Bayon Y., Sanchez Crespo M. and Nieto M. L. (1999) Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor-alpha: phosphorylation of cytosolic phospholipase A2 and transactivation of cyclooxygenase-2. J. Neurochem. 73, 16411649.
  • Hernandez M., Fuentes L., Fernandez Aviles F. J., Crespo M. S. and Nieto M. L. (2002) Secretory phospholipase A(2) elicits proinflammatory changes and upregulates the surface expression of fas ligand in monocytic cells: potential relevance for atherogenesis. Circ. Res. 90, 3845.
  • Hogyes E., Nyakas C., Kiliaan A., Farkas T., Penke B. and Luiten P. G. (2003) Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats. Neuroscience 119, 9991012.
  • Iliff J. J., Jia J., Nelson J., Goyagi T., Klaus J. and Alkayed N. J. (2010) Epoxyeicosanoid signaling in CNS function and disease. Prostaglandins Other Lipid Mediat. 115, 15301542.
  • Jaenisch R. and Bird A. (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33 (Suppl), 245254.
  • Jancic D., Lopez de Armentia M., Valor L. M., Olivares R. and Barco A. (2009) Inhibition of cAMP response element-binding protein reduces neuronal excitability and plasticity, and triggers neurodegeneration. Cereb. Cortex 19, 25352547.
  • Kam P. C. and See A. U. (2000) Cyclo-oxygenase isoenzymes: physiological and pharmacological role. Anaesthesia 55, 442449.
  • Kellom M., Basselin M., Keleshian V. L., Chen M., Rapoport S. I. and Rao J. S. (2012) Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation. BMC Neurosci. 13, 50.
  • Laflamme N., Lacroix S. and Rivest S. (1999) An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia. J. Neurosci. 19, 1092310930.
  • Leslie J. B. and Watkins W. D. (1985) Eicosanoids in the central nervous system. J. Neurosurg. 63, 659668.
  • Levenson J. M., Roth T. L., Lubin F. D., Miller C. A., Huang I.-C., Desai P., Malone L. M. and Sweatt J. D. (2006) Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J. Biol. Chem. 281, 1576315773.
  • Li E., Bestor T. H. and Jaenisch R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915926.
  • Livak K. J. and Schmittgen T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402408.
  • Lockett G. A., Wilkes F. and Maleszka R. (2010) Brain plasticity, memory and neurological disorders: an epigenetic perspective. NeuroReport, 21, 909913 910.1097/WNR.1090b1013e32833e39288.
  • Lubin F. D., Roth T. L. and Sweatt J. D. (2008) Epigenetic regulation of bdnf gene transcription in the consolidation of fear memory. J. Neurosci. 28, 1057610586.
  • Mendes C. T., Mury F. B., de Sa Moreira E., Alberto F. L., Forlenza O. V., Dias-Neto E. and Gattaz W. F. (2009) Lithium reduces Gsk3b mRNA levels: implications for Alzheimer Disease. Eur. Arch. Psychiatry Clin. Neurosci. 259, 1622.
  • Miller C. A. and Sweatt J. D. (2007) Covalent modification of DNA regulates memory formation. Neuron 53, 857869.
  • Moolwaney A. S. and Igwe O. J. (2005) Regulation of the cyclooxygenase-2 system by interleukin-1beta through mitogen-activated protein kinase signaling pathways: a comparative study of human neuroglioma and neuroblastoma cells. Brain Res. Mol. Brain Res. 137, 202212.
  • Morrison J. H. and Baxter M. G. (2012) The ageing cortical synapse: hallmarks and implications for cognitive decline. Nat. Rev. Neurosci. 13, 240250.
  • Murakami M. and Kudo I. (2002) Phospholipase A2. J. Biochem. (Tokyo) 131, 285292.
  • Murakami M., Shimbara S., Kambe T., Kuwata H., Winstead M. V., Tischfield J. A. and Kudo I. (1998) The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2. J. Biol. Chem. 273, 1441114423.
  • Murakami M., Kambe T., Shimbara S. and Kudo I. (1999) Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. J. Biol. Chem. 274, 31033115.
  • Niederberger E., Schmidtko A., Gao W., Kuhlein H., Ehnert C. and Geisslinger G. (2007) Impaired acute and inflammatory nociception in mice lacking the p50 subunit of NF-kappaB. Eur. J. Pharmacol. 559, 5560.
  • Nogami M., Takatsu A., Endo N. and Ishiyama I. (1998) Immunohistochemistry of neuron-specific enolase in neurons of the medulla oblongata from human autopsies. Acta Histochem. 100, 371382.
  • O'Banion M. K. (1999) Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology. Crit. Rev. Neurobiol. 13, 4582.
  • Okano M., Bell D. W., Haber D. A. and Li E. (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247257.
  • Penner M. R., Roth T. L., Barnes C. and Sweatt D. (2010) An epigenetic hypothesis of aging-related cognitive dysfunction. Front. Aging Neurosci. 2, In press.
  • Penner M. R., Roth T. L., Chawla M. K., Hoang L. T., Roth E. D., Lubin F. D., Sweatt J. D., Worley P. F. and Barnes C. A. (2011) Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol. Aging 32, 21982210.
  • Pereira S. G. and Oakley F. (2008) Nuclear factor-kappaB1: regulation and function. Int. J. Biochem. Cell Biol. 40, 14251430.
  • PetersenR. C. (2002) Mild cognitive impairment: transition from aging to Alzheimer's disease, in Alzheimer's Disease (IqbalK.SisodiaS. S.WinbladB. eds), pp. 141151John Wiley & Sons, LtdNew York.
  • Petersen R. C. (2004) Mild cognitive impairment as a diagnostic entity. J. Intern. Med. 256, 183194.
  • Pomara N., Block R., Domino E. F. and Gershon S. (1984) Decay in plasma lithium and normalization in red blood cell choline following cessation of lithium treatment in two elderly individuals with Alzheimer-type dementia. Biol. Psychiatry 19, 919922.
  • Rao J. S., Ertley R. N., Lee H. J., DeMar J. C. Jr, Arnold J. T., Rapoport S. I. and Bazinet R. P. (2007) n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Mol. Psychiatry 12, 3646.
  • Rao J., Rapoport S. and Kim H. (2011) Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer's disease brain. Transl. Psychiatry 1, e31.
  • Rao J. S., Keleshian V., Samuel K. and Rapoport S. I. (2012) Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients. Transl. Psychiatry 2, e132.
  • Rintala J., Seemann R., Chandrasekaran K., Rosenberger T. A., Chang L., Contreras M. A., Rapoport S. I. and Chang M. C. (1999) 85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain. NeuroReport 10, 38873890.
  • Rozovsky I., Finch C. E. and Morgan T. E. (1998) Age-related activation of microglia and astrocytes: in vitro studies show persistent phenotypes of aging, increased proliferation, and resistance to down-regulation. Neurobiol. Aging 19, 97103.
  • Sanchez-Mejia R. O., Newman J. W., Toh S. et al. (2008) Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat. Neurosci. 11, 13111318.
  • Siegmund K. D., Connor C. M., Campan M., Long T. I., Weisenberger D. J., Biniszkiewicz D., Jaenisch R., Laird P. W. and Akbarian S. (2007) DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS ONE 2, e895.
  • Tarkowski E., Andreasen N., Tarkowski A. and Blennow K. (2003) Intrathecal inflammation precedes development of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 74, 12001205.
  • Wu Y., Zhang A. Q., Wai M. S., Lai H. W., Wu S. X. and Yew D. T. (2006) Changes of apoptosis-related proteins in hippocampus of SAM mouse in development and aging. Neurobiol. Aging. 27, 782 e781–782 e710.
  • Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y. and Sun Y. E. (2010) Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 329, 444448.
  • Yang H. C., Mosior M., Johnson C. A., Chen Y. and Dennis E. A. (1999) Group-specific assays that distinguish between the four major types of mammalian phospholipase A2. Anal. Biochem. 269, 278288.
  • Yankner B. A., Lu T. and Loerch P. (2008) The aging brain. Annu. Rev. Pathol. 3, 4166.
  • Zeng Y., Tan M., Kohyama J., Sneddon M., Watson J. B., Sun Y. E. and Xie C. W. (2011) Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. J. Neurosci. 31, 1780017810.
  • Zhang A., Lorke D. E., Wu S. X. and Yew D. T. (2006) Caspase-3 immunoreactivity in different cortical areas of young and aging macaque (Macaca mulatta) monkeys. Neurosignals 15, 6473.