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Figure S1. Sequence alignment of human CRMPs.

Figure S2. SDS-PAGE of CRMP-5 WT before and after crystallization.

Figure S3. Co-expression and purification of CRMP-1 with CRMP-2 and CRMP-5.

Figure S4. Ion location in CRMP-5 ΔC Zn soak.

Figure S5. Location of mutation sites in the arm-arm interface of CRMP-5 that affect CRMP function.

Table S1. Data collection and refinement statistics for CRMP-5 Zn soak

Table S2. Sequence identity of human CRMPs.

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