Neuregulin1 signaling promotes dendritic spine growth through kalirin
Article first published online: 27 JUN 2013
© 2013 International Society for Neurochemistry
Journal of Neurochemistry
Volume 126, Issue 5, pages 625–635, September 2013
How to Cite
J. Neurochem. (2013) 126, 625–635.
- Issue published online: 23 AUG 2013
- Article first published online: 27 JUN 2013
- Accepted manuscript online: 6 JUN 2013 11:14AM EST
- Manuscript Accepted: 3 JUN 2013
- Manuscript Revised: 22 APR 2013
- Manuscript Received: 24 JAN 2013
- NIH-NIMH. Grant Numbers: R01MH071316, R01MH097216
- National Alliance for Research on Schizophrenia and Depression (NARSAD)
- Kirschstein National Research Service Awards. Grant Numbers: 1F31AG031621-01A2, 1F31MH085362
- NIH. Grant Numbers: R01 MH 071533, R01 AG027224
- VHA. Grant Number: I01 BX000452
Figure S1. (a) Cultured hippocampal neurons expressing GFP were treated with vehicle or with 5 nm NRG1.
Figure S2. (a) High magnification images of dendrites of cultured cortical neurons generated from wild type (WT) or KALRN knockout (KO) mice, expressing GFP, with or without NRG1 treatment for 3-days.
Figure S3. hEK293 were mock transfected or transfected with erbB4 cDNA for 2-days.
Figure S4. NRG1 and erbB4 both increase spine size and knocking down kalirin blocks the ability of NRG1 and erbB4 to regulate spine size.
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