These authors contributed equally to this work.
Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance
Article first published online: 21 AUG 2013
© 2013 International Society for Neurochemistry
Journal of Neurochemistry
Volume 128, Issue 1, pages 162–172, January 2014
How to Cite
J. Neurochem. (2014) 128, 162–172.
- Issue published online: 17 DEC 2013
- Article first published online: 21 AUG 2013
- Accepted manuscript online: 29 JUL 2013 09:56AM EST
- Manuscript Accepted: 24 JUL 2013
- Manuscript Revised: 22 JUL 2013
- Manuscript Received: 26 FEB 2013
- National Institutes of Health. Grant Numbers: AG028679, AG031852
- P30 AG028383
|jnc12380-sup-0001-FigS1.pdf||application/PDF||1038K||Figure S1. Western blot analysis of purified leptin incubated in human CSF collected from two individuals, case A and case B, shows no degradation of either the monomer or dimer band even after 4 h incubation at 37°C, mimicking the longest post-mortem interval of the subjects used for the leptin RIA analysis (a). The leptin receptor antibody, which detects NFT in AD brain by immunocytochemistry, detects the full length Ob-Rb at approximately 125kDa.|
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