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Figure S1. Molecular characterization of the cholesterol/Aβ22-35 complex.

Figure S2. Hydrogen-bond-driven oligomerization of Aβ22-35.

Figure S3. Lack of effect of Aβ22-35 in Ca2+-free extracellular conditions.

Figure S4. Helical wheel diagram of Aβ22-35 in the octameric channel.

Figure S5. Methyl-β-cyclodextrin decrease cholesterol level in SH-SY5Y cells.

Table S1. Energetics of Aβ22-35 dimerization.

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