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Appendix S1.Supplementary Materials and methods.

Figure S1. 5-Nonyloxytryptamine oxalate (5-NOT) competes with colominic acid for binding to the PSA-specific antibody 735 (mAb 735).

Figure S2. Representative images of (a) cerebellar neurons, (b) hippocampal neurons, (c) motor neurons and (d) Schwann cells bearing neurites/processes.

Figure S3. Nonyloxytryptamine stimulates myelination of dorsal root ganglion neurons in vitro.

Figure S4. Nonyloxytryptamine treatment does not influence the viability of IMR-32 cells.

Figure S5. MAP2 expression is down-regulated in IMR-32 cells after 5-NOT treatment.

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