Figure S1. Binding of KIBRA wt, and point mutants in the two serine residues that can be phosphorylated by PKMζ in vitro.

Figure S2. PKMζ is proteasomally degraded in neuronal cells.

Figure S3. Alanin scan of PKMζ binding motif.

Figure S4. Efficacy of different KIBRA siRNAs in HEK cells and primary neurons.

Figure S5. Open field analysis of rats after knock-down of KIBRA with an AAV vector.

Figure S6. Generation of KIBRA knock-out mice.

Figure S7. Open field and holeboard analysis of KIBRA knock-out mice.

Figure S8. EGFP-KIB956-975 stabilizes endogenous PKMζ protein in primary cortical neurons.

Figure S9. Spatial memory performance in rats expressing a PKMζ-binding peptide – EGFP fusion in the hippocampus.

Figure S10. Primary neurons infected with an AAV vector encoding a KIBRA-EGFP fusion protein.

Table S1. Additional oligonucleotides used for mapping the PKMζ interaction site on KIBRA.

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.