Heat shock protein 70 induction by valproic acid delays photoreceptor cell death by N-methyl-N-nitrosourea in mice
Article first published online: 22 MAY 2014
© 2014 International Society for Neurochemistry
Journal of Neurochemistry
Volume 130, Issue 5, pages 707–719, September 2014
How to Cite
J. Neurochem. (2014) 130, 707–719.
- Issue published online: 20 AUG 2014
- Article first published online: 22 MAY 2014
- Accepted manuscript online: 29 APR 2014 04:41AM EST
- Manuscript Accepted: 28 APR 2014
- Manuscript Revised: 18 APR 2014
- Manuscript Received: 10 JAN 2014
- Ministry of Education, Culture, Sports, Science and Technology of Japan. Grant Numbers: 25462753, 25640008
Figure S1. HSP70 induction by VPA canceled the decrease of recoverin protein levels by MNU.
Figure S2. VPA after 6 h of MNU injection slightly decreased TUNEL-positive cells by MNU. Microscopical images of retina treated with (a) vehicle, (b) MNU (3 days), (c) MNU + VPA (pre-treatment of MNU), (d) MNU + VPA (post-treatment of MNU). Scale bar = 50 μm.
Figure S3. Schematic diagram for HSP70 induction by VPA protecting against photoreceptor cell death.
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