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Figure S1. The mitochondria fraction was not contaminated by other organelles PDI (ER marker), GM130 (Golgi apparatus marker), and LC3 (lysosomal marker) levels in the whole cell lysates, cytoplasm, or mitochondria fraction of HEK293/wt cells were detected by western blotting.

Figure S2. PTPA knockdown decreased ATP level HEK293/wt cells were transfected with ssiPTPA or siPTPA plasmid for 48 h, the intracellular ATP level was measured by ATP detection kit. The data were expressed as mean ± SD. *< 0.05 versus ssiPTPA.

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