Joint senior authors
HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice
Article first published online: 18 JUL 2014
© 2014 International Society for Neurochemistry
Journal of Neurochemistry
Volume 131, Issue 2, pages 177–189, October 2014
How to Cite
J. Neurochem. (2014) 131, 177–189.
- Issue published online: 17 OCT 2014
- Article first published online: 18 JUL 2014
- Accepted manuscript online: 26 JUN 2014 01:14PM EST
- Manuscript Accepted: 23 JUN 2014
- Manuscript Revised: 19 JUN 2014
- Manuscript Received: 28 DEC 2013
- Dunhill Medical Trust
- Foundation Leducq
- Wellcome Trust
- British Heart Foundation
- Biotechnological and Biological Research Council
- European Union
- Henry Smith Medical Research
- National Institute for Health Research
Figure S1. Summary of rCBF before, during and after MCAO in mice. rCBF dropped significantly below 30% of baseline levels upon MCAO in each mouse in all experimental groups, and returned towards baseline rapidly after reperfusion.
Figure S2. Summary of mouse temperature at baseline and after MCAO.
Figure S3. Apoptotic cell detection on 6-μm brain sections from mice receiving IOX3/vehicle immediately before the surgery.
Figure S4. Effect of IOX3 on RBE4 cell viability.
Table S1. A list of primers used for RT-PCR.
Table S2. Mouse body weights at baseline, weight loss and mortality 24 h after the MCAO.
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