SEARCH

SEARCH BY CITATION

References

  • Allen J. A., Halverson-Tamboli R. A. and Rasenick M. M. (2007) Lipid raft microdomains and neurotransmitter signalling. Nat. Rev. Neurosci. 8, 128140.
  • Bedia C., Camacho L., Casas J., Abad J. L., Delgado A., Van Veldhoven P. P. and Fabrias G. (2009) Synthesis of a fluorogenic analogue of sphingosine-1-phosphate and its use to determine sphingosine-1-phosphate lyase activity. ChemBioChem 10, 820822.
  • Berdyshev E. V., Gorshkova I. A., Garcia J. G., Natarajan V. and Hubbard W. C. (2005) Quantitative analysis of sphingoid base-1-phosphates as bisacetylated derivatives by liquid chromatography-tandem mass spectrometry. Anal. Biochem. 339, 129136.
  • Botto L., Beretta E., Bulbarelli A., Rivolta I., Lettiero B., Leone B. E., Miserocchi G. and Palestini P. (2008) Hypoxia-induced modifications in plasma membranes and lipid microdomains in A549 cells and primary human alveolar cells. J. Cell. Biochem. 105, 503513.
  • Breen P., Joseph N., Thompson K. et al. (2013) Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells. Anticancer Res. 33, 7784.
  • Burek M., Salvador E. and Forster C. Y. (2012) Generation of an immortalized murine brain microvascular endothelial cell line as an in vitro blood brain barrier model. J. Vis. Exp. 66, e4022.
  • Camos S. and Mallolas J. (2010) Experimental models for assaying microvascular endothelial cell pathophysiology in stroke. Molecules 15, 91049134.
  • Dasgupta S., Wang G. and Yu R. K. (2011) Sulfoglucuronosyl paragloboside promotes endothelial cell apoptosis in inflammation: elucidation of a novel glycosphingolipid-signaling pathway. J. Neurochem. 119, 749759.
  • Devlin C. M., Lahm T., Hubbard W. C., Van Demark M., Wang K. C., Wu X., Bielawska A., Obeid L. M., Ivan M. and Petrache I. (2011) Dihydroceramide-based response to hypoxia. J. Biol. Chem. 286, 3806938078.
  • Dohgu S., Nishioku T., Sumi N., Takata F., Nakagawa S., Naito M., Tsuruo T., Yamauchi A., Shuto H. and Kataoka Y. (2007) Adverse effect of cyclosporin A on barrier functions of cerebral microvascular endothelial cells after hypoxia-reoxygenation damage in vitro. Cell. Mol. Neurobiol. 27, 889899.
  • Go A. S., Mozaffarian D., Roger V. L. et al. (2013) Heart disease and stroke statistics–2013 update: a report from the American Heart Association. Circulation 127, e6e245.
  • Hankin J. A., Farias S. E., Barkley R. M., Heidenreich K., Frey L. C., Hamazaki K., Kim H. Y. and Murphy R. C. (2011) MALDI mass spectrometric imaging of lipids in rat brain injury models. J. Am. Soc. Mass Spectrom. 22, 10141021.
  • Hisaki H., Okazaki T., Kubota M., Nakane M., Fujimaki T., Nakayama H., Nakagomi T., Tamura A. and Masuda H. (2008) L-PDMP improves glucosylceramide synthesis and behavior in rats with focal ischemia. Neurol. Res. 30, 979984.
  • Ito S., Iwaki S., Koike K. et al. (2013) Increased plasma sphingosine-1-phosphate in obese individuals and its capacity to increase the expression of plasminogen activator inhibitor-1 in adipocytes. Coron. Artery Dis. 24, 642650.
  • Kilkus J., Goswami R., Testai F. D. and Dawson G. (2003) Ceramide in rafts (detergent-insoluble fraction) mediates cell death in neurotumor cell lines. J. Neurosci. Res. 72, 6575.
  • Kilkus J. P., Goswami R., Dawson S. A., Testai F. D., Berdyshev E. V., Han X. and Dawson G. (2008) Differential regulation of sphingomyelin synthesis and catabolism in oligodendrocytes and neurons. J. Neurochem. 106, 17451757.
  • Kok J. W., Nikolova-Karakashian M., Klappe K., Alexander C. and Merrill A. H., Jr (1997) Dihydroceramide biology. Structure-specific metabolism and intracellular localization. J. Biol. Chem. 272, 2112821136.
  • Liu J. R., Ding M. P., Wei E. Q., Luo J. H., Song Y., Huang J. Z., Ge Q. F., Hu H. and Zhu L. J. (2005) GM1 stabilizes expression of NMDA receptor subunit 1 in the ischemic hemisphere of MCAo/reperfusion rat. J. Zhejiang Univ. Sci. B 6, 254258.
  • Liu Y. Y., Patwardhan G. A., Xie P., Gu X., Giuliano A. E. and Cabot M. C. (2011) Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma. Int. J. Oncol. 39, 425431.
  • Maalouf K., Jia J., Rizk S., Brogden G., Keiser M., Das A. and Naim H. Y. (2010) A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV. J. Inherit. Metab. Dis. 33, 445449.
  • Marquez M. G. and Sterin-Speziale N. B. (2008) Is DRM lipid composition relevant in cell-extracellular matrix adhesion structures? Cell Adh. Migr. 2, 180183.
  • Michel C., van Echten-Deckert G., Rother J., Sandhoff K., Wang E. and Merrill A. H., Jr (1997) Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide. J. Biol. Chem. 272, 2243222437.
  • Mikami T., Kashiwagi M., Tsuchihashi K., Akino T. and Gasa S. (1998) Substrate specificity and some other enzymatic properties of dihydroceramide desaturase (ceramide synthase) in fetal rat skin. J. Biochem. 123, 906911.
  • Muruganandam A., Herx L. M., Monette R., Durkin J. P. and Stanimirovic D. B. (1997) Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood-brain barrier. FASEB J. 11, 11871197.
  • Nagababu E., Usatyuk P. V., Enika D., Natarajan V. and Rifkind J. M. (2009) Vascular endothelial barrier dysfunction mediated by amyloid-beta proteins. J. Alzheimers Dis. 17, 845854.
  • Nakane M., Kubota M., Nakagomi T., Tamura A., Hisaki H., Shimasaki H. and Ueta N. (2000) Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus. Neurosci. Lett. 296, 8992.
  • Novgorodov S. A. and Gudz T. I. (2009) Ceramide and mitochondria in ischemia/reperfusion. J. Cardiovasc. Pharmacol. 53, 198208.
  • Novgorodov S. A. and Gudz T. I. (2011) Ceramide and mitochondria in ischemic brain injury. Int. J. Biochem. Mol. Biol. 2, 347361.
  • Olmez I. and Ozyurt H. (2012) Reactive oxygen species and ischemic cerebrovascular disease. Neurochem. Int. 60, 208212.
  • Parton R. G. and Simons K. (2007) The multiple faces of caveolae. Nat. Rev. Mol. Cell Biol. 8, 185194.
  • Qi Y., Jamindar T. M. and Dawson G. (1995) Hypoxia alters iron homeostasis and induces ferritin synthesis in oligodendrocytes. J. Neurochem. 64, 24582464.
  • Qin J., Testai F. D., Dawson S., Kilkus J. and Dawson G. (2009) Oxidized phosphatidylcholine formation and action in oligodendrocytes. J. Neurochem. 110, 13881399.
  • Qin J., Berdyshev E., Goya J., Natarajan V. and Dawson G. (2010) Neurons and oligodendrocytes recycle sphingosine 1-phosphate to ceramide: significance for apoptosis and multiple sclerosis. J. Biol. Chem. 285, 1413414143.
  • Siddique M. M., Li Y., Wang L., Ching J., Mal M., Ilkayeva O., Wu Y. J., Bay B. H. and Summers S. A. (2013) Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling. Mol. Cell. Biol. 33, 23532369.
  • Sprenger R. R., Fontijn R. D., van Marle J., Pannekoek H. and Horrevoets A. J. (2006) Spatial segregation of transport and signalling functions between human endothelial caveolae and lipid raft proteomes. Biochem. J. 400, 401410.
  • Stiban J., Fistere D. and Colombini M. (2006) Dihydroceramide hinders ceramide channel formation: Implications on apoptosis. Apoptosis 11, 773780.
  • Testai F. D., Landek M. A. and Dawson G. (2004a) Regulation of sphingomyelinases in cells of the oligodendrocyte lineage. J. Neurosci. Res. 75, 6674.
  • Testai F. D., Landek M. A., Goswami R., Ahmed M. and Dawson G. (2004b) Acid sphingomyelinase and inhibition by phosphate ion: role of inhibition by phosphatidyl-myo-inositol 3,4,5-triphosphate in oligodendrocyte cell signaling. J. Neurochem. 89, 636644.
  • Testai F. D., Hillmann M., Amin-Hanjani S., Gorshkova I., Berdyshev E., Gorelick P. B. and Dawson G. (2012) Changes in the cerebrospinal fluid ceramide profile after subarachnoid hemorrhage. Stroke 43, 20662070.
  • Vaskovsky V. E., Kostetsky E. Y. and Vasendin I. M. (1975) A universal reagent for phospholipid analysis. J. Chromatogr. 114, 129141.
  • Wiesner D. A., Kilkus J. P., Gottschalk A. R., Quintans J. and Dawson G. (1997) Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL. J. Biol. Chem. 272, 98689876.
  • Yamagishi K., Mishima K., Ohgami Y., Iwasaki K., Jimbo M., Masuda H., Igarashi Y., Inokuchi J. and Fujiwara M. (2003) A synthetic ceramide analog ameliorates spatial cognition deficit and stimulates biosynthesis of brain gangliosides in rats with cerebral ischemia. Eur. J. Pharmacol. 462, 5360.
  • Yamaoka S., Miyaji M., Kitano T., Umehara H. and Okazaki T. (2004) Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells. J. Biol. Chem. 279, 1868818693.
  • Yan F. L., Zheng Y. and Zhao F. D. (2008) Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia. Acta Neuropathol. 116, 529535.
  • Yang J. P., Liu H. J. and Liu X. F. (2010) VEGF promotes angiogenesis and functional recovery in stroke rats. J. Invest. Surg. 23, 149155.
  • Yu J., Novgorodov S. A., Chudakova D., Zhu H., Bielawska A., Bielawski J., Obeid L. M., Kindy M. S. and Gudz T. I. (2007) JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction. J. Biol. Chem. 282, 2594025949.
  • Zheng W., Kollmeyer J., Symolon H. et al. (2006) Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochim. Biophys. Acta 1758, 18641884.
  • del Zoppo G. J. (2010) The neurovascular unit in the setting of stroke. J. Intern. Med. 267, 156171.