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Twenty years of Alzheimer’s disease-causing mutations (pages 3–8)Alison Goate and John Hardy
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07575.x
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Proteolytic processing of Alzheimer’s β-amyloid precursor protein (pages 9–21)Han Zhang, Qilin Ma, Yun-wu Zhang and Huaxi Xu
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07519.x
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You have free access to this content
Identification and biology of α-secretase (pages 34–45)Valérie Vingtdeux and Philippe Marambaud
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07477.x
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Activation of α-secretase cleavage (pages 46–54)Rolf Postina
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07459.x
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Identification and biology of β-secretase (pages 55–61)Patty C. Kandalepas and Robert Vassar
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07512.x
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Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer’s Disease (pages 62–70)Xiulian Sun, Kelley Bromley-Brits and Weihong Song
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07515.x
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Developing β-secretase inhibitors for treatment of Alzheimer’s disease (pages 71–83)Arun K. Ghosh, Margherita Brindisi and Jordan Tang
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07476.x
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Assembly of the presenilin γ-/ε-secretase complex (pages 84–88)P. St George-Hyslop and P. E. Fraser
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07505.x
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γ-Secretase inhibitors and modulators for Alzheimer’s disease (pages 89–98)Michael S. Wolfe
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07501.x
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Functions of Aβ, sAPPα and sAPPβ : similarities and differences (pages 99–108)Stéphanie Chasseigneaux and Bernadette Allinquant
Article first published online: 7 DEC 2011 | DOI: 10.1111/j.1471-4159.2011.07584.x
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The physiology of the β-amyloid precursor protein intracellular domain AICD (pages 109–124)Raphaëlle Pardossi-Piquard and Frédéric Checler
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07475.x
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Soluble Aβ oligomer production and toxicity (pages 125–139)Megan E. Larson and Sylvain E. Lesné
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07478.x
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You have free access to this content
The role of metallobiology and amyloid-β peptides in Alzheimer’s disease (pages 149–166)Blaine R. Roberts, Timothy M. Ryan, Ashley I. Bush, Colin L. Masters and James A. Duce
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07500.x
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Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer’s disease? (pages 167–185)Natalia N. Nalivaeva, Caroline Beckett, Nikolai D. Belyaev and Anthony J. Turner
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07510.x
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‘Clinical trials in Alzheimer’s disease’: immunotherapy approaches (pages 186–193)Julien Delrieu, Pierre Jean Ousset, Céline Caillaud and Bruno Vellas
Article first published online: 28 NOV 2011 | DOI: 10.1111/j.1471-4159.2011.07458.x