Tranexamic acid: an important adjuvant in the treatment of melasma
Article first published online: 26 FEB 2013
© 2013 Wiley Periodicals, Inc.
Journal of Cosmetic Dermatology
Volume 12, Issue 1, pages 57–66, March 2013
How to Cite
Tse, T. W. and Hui, E. (2013), Tranexamic acid: an important adjuvant in the treatment of melasma. Journal of Cosmetic Dermatology, 12: 57–66. doi: 10.1111/jocd.12026
- Issue published online: 26 FEB 2013
- Article first published online: 26 FEB 2013
- Manuscript Accepted: 13 SEP 2012
- tranexamic acid;
- postinflammatory hyper-pigmentation
This article reviews an old drug tranexamic acid to its new use in the treatment of melasma. Its mechanism of preventing the activation of melanocyte from UV light, hormone and injured kerationcyte through the inhibition of the plasminogen activator system will be explored. The detail usage for such indication and its safety profile will also be thoroughly evaluated.