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Tranexamic acid: an important adjuvant in the treatment of melasma


Correspondence: T W Tse, 14/F Manning House, 48 Queen's Road, Central, Hong Kong. E-mail:


This article reviews an old drug tranexamic acid to its new use in the treatment of melasma. Its mechanism of preventing the activation of melanocyte from UV light, hormone and injured kerationcyte through the inhibition of the plasminogen activator system will be explored. The detail usage for such indication and its safety profile will also be thoroughly evaluated.