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Longitudinal evaluation of cryolipolysis efficacy: two case studies


Correspondence: E F Bernstein, M.D., M.S.E., 32 Parking Plaza, Suite 200, Ardmore, PA 19003, USA. E-mail:


Cryolipolysis treatment, or cold-induced destruction of adipocytes, provides a noninvasive option for localized subcutaneous fat reduction without damaging the overlying skin or adjacent structures. This case study examines the long-term visibility of fat layer reduction subsequent to cryolipolysis treatment, through longitudinal evaluation. Two male subjects were unilaterally treated on one flank. Baseline and postprocedure photographs (at 2 or 5 years) of the treated and contralateral untreated flanks display durable results despite natural fluctuations in body weight.