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Clinical observation and nursing care on the prevention of abdominal organ cluster transplantation rejection

Authors

  • Hongxia Zhang BSN,

    Co-Chief Superintendent Nurse
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Lifen Chen MSN,

    Chief Superintendent Nurse, Corresponding author
    • Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Guangxiang Gu MD,

    Resident Physician
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Zhiyong Guo PhD,

    Doctor-in-Charge and Lecturer
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Fengqiu Gong BSN,

    Co-Chief Superintendent Nurse
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Shuwen Wu BSN,

    Co-Chief Superintendent Nurse
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Xiaoyuan Zhang BSN,

    Chief Superintendent Nurse
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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  • Xiaoshun He PhD

    Chief Physician and Professor
    1. Department of Organ transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
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Correspondence: Lifen Chen, Department of Organ Transplantation, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China. Telephone: +86 020 8730 6082.

E-mail: chlife1121@126.com

Abstract

Aims and objectives

To investigate the clinical characteristics of rejection after upper abdominal cluster transplantation.

Background

Abdominal organ cluster transplantation is used to treat multiple abdominal organ diseases. Delay in monitoring and treatment can lead to graft failure.

Design

A descriptive study.

Methods

Data collected from eight patients who underwent abdominal organ cluster transplantation from May 2004–March 2009 in our hospital were retrospectively assessed. The clinical manifestations of graft rejection and variations in characteristics associated with graft function were analysed.

Results

In all eight cases, graft function recovered successfully without rejection during the perioperative period. In one case, liver graft rejection occurred 1·5 months postoperatively, but dose adjustment of the anti-rejection drugs provided symptom relief.

Conclusions

Rejection can be prevented and cured successfully through monitoring and early detection of rejection characteristics by the nursing staff.

Relevance to clinical practice

With the increase of awareness and knowledge on the clinical observation and nursing care, the rate of transplantation rejection decreased among abdominal cluster transplant patients.

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