The first and second authors contributed equally to this work.
The effect of continuous nursing intervention guided by chronotherapeutics on ambulatory blood pressure of older hypertensive patients in the community
Article first published online: 7 JAN 2014
© 2014 John Wiley & Sons Ltd
Journal of Clinical Nursing
Volume 23, Issue 15-16, pages 2247–2255, August 2014
How to Cite
Cheng, M., Cheng, S.-L., Zhang, Q., Jiang, H., Cong, J.-Y., Zang, X.-Y. and Zhao, Y. (2014), The effect of continuous nursing intervention guided by chronotherapeutics on ambulatory blood pressure of older hypertensive patients in the community. Journal of Clinical Nursing, 23: 2247–2255. doi: 10.1111/jocn.12502
- Issue published online: 12 JUL 2014
- Article first published online: 7 JAN 2014
- Manuscript Accepted: 3 SEP 2013
- Tianjin Medical University
- ambulatory blood pressure monitoring;
- continuous nursing intervention;
- primary hypertension
Aims and objectives
To explore the effect of continuous nursing intervention guided by chronotherapeutics so as to provide the easy, noninvasive, effective and acceptable intervention for older hypertensive patients in the community.
Many researchers studied the effect of administration at different times on blood pressure control and circadian rhythm. However, the individual administrative time was set ambiguously in previous studies.
A semi-experimental study.
In the study, 90 eligible patients were recruited and separated into three groups randomly, which were the control group, intervention group A (behaviour and chronotherapy intervention) and intervention group B (behaviour intervention). At 6 and 12 months after the study, the intervention groups were measured 24-hour ambulatory blood pressure monitoring.
There were significant differences in ambulatory blood pressure monitoring parameters of the two intervention groups at different measurement times, and there were interaction between measurement time and different groups. The number of patients with dipper increased and reverse dipper decreased in group A as the intervention applied. There were statistical differences between two groups. The number of patients with morning surge in group A decreased more, and there were statistical differences between two groups at six months after the intervention.
The behaviour and chronotherapy intervention based on the patients' ambulatory blood pressure monitoring can control casual blood pressure much better and last longer, which can also improve patients' indexes of ambulatory blood pressure monitoring better than behaviour intervention only. The behaviour and chronotherapy intervention can increase patients' nocturnal blood pressure drop, increase the number of patients with dipper and decrease reverse dipper, and improve blood pressure surge in the morning.
Relevance to clinical practice
Nurses can use continuous nursing intervention guided by chronotherapeutics to help improve hypertension of older patients better in the community.