Conflict of interest: The authors declare no conflict of interest.
Placental mesenchymal dysplasia differentially diagnosed from molar pregnancy by 3-D inversion mode rendering: A case report
Article first published online: 19 SEP 2013
© 2013 The Authors. Journal of Obstetrics and Gynaecology Research © 2013 Japan Society of Obstetrics and Gynecology
Journal of Obstetrics and Gynaecology Research
Volume 40, Issue 1, pages 284–287, January 2014
How to Cite
Minekawa-Mehandjiev, R., Masuda, K., Yamamoto, K., Miura, K., Nakayama, M. and Murata, Y. (2014), Placental mesenchymal dysplasia differentially diagnosed from molar pregnancy by 3-D inversion mode rendering: A case report. Journal of Obstetrics and Gynaecology Research, 40: 284–287. doi: 10.1111/jog.12152
- Issue published online: 1 JAN 2014
- Article first published online: 19 SEP 2013
- Manuscript Accepted: 16 APR 2013
- Manuscript Received: 24 JAN 2013
- inversion mode;
- partial molar pregnancy;
- placental mesenchymal dysplasia
Placental mesenchymal dysplasia (PMD) is a rare placental vascular anomaly which resembles partial molar pregnancy by 2-D ultrasonography. It is challenging but clinically important to distinguish between them in order to avoid unnecessary termination of pregnancy. A patient was referred to our centre at 13 weeks of gestation and 2-D ultrasound of the placenta showed a widespread vesicular pattern mixed with normal appearing placenta. Amniotic fluid volume was normal, and the fetus appeared to be an appropriate size for gestation without obvious structural abnormalities. 3-D reconstruction imaging of the placenta showed a large multi-cystic area arising from the chorionic plate which was adjacent to normal-appearing placenta. 3-D imaging rendered with ‘inversion mode’ revealed multiple fluid-filled structures with different sizes and appearances. Her serum hCG level was slightly elevated. All findings taken together, we suspected PMD rather than partial molar pregnancy. Histological examinations of the placenta after termination at 15 weeks confirmed the diagnosis.