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Associations for birthweight of twin pairs in south India




The aim of this study was to determine the distribution and associations of birthweight in twin pairs among a population of pregnant women in south India.

Material and Methods

This was a retrospective case record analysis of 705 twin pair pregnancies during the period 2008–2012. Associations of birthweight with maternal age, parity, pregnancy-induced hypertension (PIH), gestational diabetes, obesity, chorionicity and sex of the twin pairs was explored using bivariate and multivariate analysis.


The median birthweight (4250 g, interquartile range 3530–4810) of dichorionic twins was significantly higher (P < 0.0001) than monochorionic twins (3880 g, interquartile range 3000–4380). Birthweight was associated with chorionicity (t = 4.04, P < 0.001), obesity (t = 2.44, P = 0.03), nulliparity (t = −2.87, P = 0.004), and PIH (t = −2.11, P = 0.04) in a multivariate linear regression model. Birthweights did not differ significantly between female–male and female–female pairs (t = 0.11, P = 0.81), female–male and male–male pairs (t = −0.62, P = 0.54) or female–female and male–male pairs (t = −0.78, P = 0.43) in a multivariate linear regression model. The highest birthweight of the twin pair did not differ significantly (t = 1.27, P = 0.21) by sex of the twin.


Birthweight of twins was significantly associated with chorionicity, obesity, PIH and nulliparity in this population. A potential masculinization effect was not found as the total birthweights did not differ significantly by sex of the twin pairs.