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Appendix S1. Supplementary information on Material and Methods and Results.

Figure S1. Effects of n-3 fatty acid (FA) supplementation for 6 months on plasma (top) and CSF (bottom) concentrations of linoleic, arachidonic, EPA, EPA, their intermediary 22 : 5 n-3 (DPA n-3) and concentrations of all n-3 FA. Data are given as relative concentrations of the FAs.

Table S1. Data on inflammatory and dementia biomarkers in CSF and measure of cognition.

Table S2. Mean (and 95% CI) values for CSF fatty acids at start (before supplementation with a DHA rich n-3 FA preparation) in relation to values of cognitive functions, assessed by the Mini-Mental State Examination (MMSE).

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