Letter to the Editor
Response to Letter to the Editor ‘Red cell distribution width in patients with atrial fibrillation’
Article first published online: 25 FEB 2014
© 2013 The Association for the Publication of the Journal of Internal Medicine
Journal of Internal Medicine
Volume 275, Issue 5, page 544, May 2014
How to Cite
Adamsson Eryd, S., Borné, Y., Melander, O., Persson, M., Gustav Smith, J., Hedblad, B. and Engström, G. (2014), Response to Letter to the Editor ‘Red cell distribution width in patients with atrial fibrillation’. Journal of Internal Medicine, 275: 544. doi: 10.1111/joim.12181
- Issue published online: 18 APR 2014
- Article first published online: 25 FEB 2014
- Accepted manuscript online: 17 DEC 2013 12:34PM EST
We thank the authors for their acknowledgement and interest in our study .
RDW is a new and easily available risk marker for adverse cardiovascular outcomes, and we agree that this may encourage a wider use in clinical practice. As pointed out by Balta et al. , the underlying causal links are unclear. The causal links could hypothetically involve some of the factors mentioned by Balta et al. , but also properties of the red cells per se.
Dr Balta et al. also ask for clarification of time frame for analysis of RDW. The analyses were performed consecutively at the time of the screening examination. The samples of heparinized blood were delivered one by one to the central laboratory of Malmö Hospital for analysis. The samples were immediately analysed using the SYSMEX K1000 fully automated assay. The analysis took 45 s. Normally, it took 10–20 min from blood sampling to analysis. The samples were stored in room temperature before analysis. Hence, it seems unlikely that the analytical procedures could be related to future atrial fibrillation and influence the results.
Conflict of interest statement
No conflict of interest to declare.
- 2Red cell distribution width in patients with atrial fibrillation. J Intern Med 2013., , , , .