These authors contributed equally to this work and should both be considered first authors.
Diagnostic and prognostic value of circulating microRNAs in patients with acute chest pain
Version of Record online: 27 MAR 2014
© 2013 The Association for the Publication of the Journal of Internal Medicine
Journal of Internal Medicine
Volume 277, Issue 2, pages 260–271, February 2015
How to Cite
Centre de Recherche Public de la Santé, Luxembourg; University Hospital Basel, Basel; Centre Hospitalier, Luxembourg). Diagnostic and prognostic value of circulating microRNAs in patients with acute chest pain. J Intern Med 2015; 277: 260–271., , , , , , , , , , , (
- Issue online: 26 JAN 2015
- Version of Record online: 27 MAR 2014
- Accepted manuscript online: 17 DEC 2013 12:34PM EST
- Ministry of Culture, Higher Education and Research of Luxembourg
- National Research Fund of Luxembourg
Figure S1 Presentation values of 6 miRNAs in (a) patients with AMI (n= 224) and without AMI (n=931); (b) patients with STEMI (n= 45) and NSTEMI (n=179).
Figure S2 ROC curves displaying diagnostic accuracy for (a) 6 miRNAs, (b–c) miR-208b and miR-499 in comparison and combination with a conventional (cTnT4, Roche Diagnostic) and high-sensitivity cardiac Troponin assay (hs-cTnT, Roche Diagnostics), (d) 6 miRNAs in early presenters (presenting within 3 hours from symptom onset).
Figure S3 Kaplan Meier curves for survival in all acute chest pain patients displaying cumulative survival during short-term follow-up (30 days) and long-term follow-up (730 days), subdivided into 2 groups according to optimal cut-off (-10.38) by Youden index (sensitivity of 31.8%, specificity of 86.2%). Log-rank values were employed to assess statistical significance. miRNA values are log-transformed.
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