These authors contributed equally to this paper.
Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease
Version of Record online: 2 MAR 2014
© 2014 The Association for the Publication of the Journal of Internal Medicine
Journal of Internal Medicine
Volume 276, Issue 5, pages 470–485, November 2014
How to Cite
Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease. J Intern Med 2014; 276: 470–485., , , , , , , , , , , , (Second Military Medical University, Shanghai; University of Zurich, Zurich; University of Washington School of Medicine, Seattle, WA; University of Washington, Seattle, WA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; University Hospital Zurich, Zurich).
- Issue online: 24 OCT 2014
- Version of Record online: 2 MAR 2014
- Accepted manuscript online: 4 FEB 2014 12:44PM EST
- National High Technology Research and Development Program. Grant Number: 2007AA02Z3Z1
- National Natural Science Foundation of China. Grant Numbers: 30971368, 30871179
- Shanghai Key Discipline Project. Grant Number: B902
- Major National Science and Technology Project. Grant Number: 2009ZX09102
- Shanghai Science and Technology Commission Major Research Project. Grant Number: 11431920800
- Zhejiang Provincial Program for the Cultivation of High-level Innovative Health Talents
- Swiss National Science Foundation. Grant Numbers: 0954070200, 09ZR1410400, P30 HD02274
- Qianjiang Talents Project of Science and Technology Department in Zhejiang Province
- Shanghai International Science and Technology Cooperation Fund. Grant Number: 0954070200
- Shanghai Science and Technology Committee. Grant Number: 09ZR1410400
- National Institute of Child Health and Human Development. Grant Number: P30 HD02274
- Swiss National Science Foundation. Grant Numbers: 320030-144093, 310030-132597
FigureS1. Gene ontology analysis of glycoprotein identified in human ADPKD urine.
FigureS2. Characterization of CFBin human urine.
Figure S3. Characterization of SERPING1, C9, C1RL, CD55 and CD59in human urine.
Table S1. Glycoproteins and Glycopeptides Identified in Human Urine.
Table S2. Glucoproteins identified in human urine of previous investigations.
Table S3. Glycopeptides unannotated by current database.
Table S4. The 6 complement-related proteins identified by multiple peptides.
Table S5. Human CFB,SERPING1,C9,C1RL,CD55 and CD59peptides identified by mass spectrometry in urine.
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.