Trends in 28-day and 1-year mortality rates in patients hospitalized for a first acute myocardial infarction in Norway during 2001–2009: a “Cardiovascular disease in Norway” (CVDNOR) project

Authors

  • E. Sulo,

    Corresponding author
    1. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
    • Correspondence: Enxhela Sulo, Department of Global Public Health and Primary Care, N-5020 Bergen, Norway.

      (fax: + 47 55 58 61 30; e-mail: Enxhela.Sulo@igs.uib.no).

    Search for more papers by this author
  • S. E. Vollset,

    1. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
    2. Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway
    Search for more papers by this author
  • O. Nygård,

    1. Section for Cardiology, Department of Clinical Science, University of Bergen, Bergen, Norway
    2. Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
    Search for more papers by this author
  • G. Sulo,

    1. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
    Search for more papers by this author
  • J. Igland,

    1. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
    Search for more papers by this author
  • G. M. Egeland,

    1. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
    2. Department of Health Registries, Norwegian Institute of Public Health, Bergen, Norway
    Search for more papers by this author
  • M. Ebbing,

    1. Department of Health Registries, Norwegian Institute of Public Health, Bergen, Norway
    Search for more papers by this author
  • G. S. Tell

    1. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
    2. Department of Health Registries, Norwegian Institute of Public Health, Bergen, Norway
    Search for more papers by this author

Abstract

Objective

The aim of this study was to investigate the trends in 28-day and 1-year mortality rates in patients hospitalized for a first acute myocardial infarction (AMI) in Norway during the period 2001–2009. Potential age group and gender differences in these trends were also examined.

Design, subjects and setting

In this retrospective nationwide cohort study, patients hospitalized for a first AMI between 2001 and 2009 were identified in the Cardiovascular Disease in Norway 1994–2009 (CVDNOR) project and followed for 1 year.

Main outcome measures

Trends in 28-day and 1-year mortality [both all-cause and cardiovascular disease (CVD) mortality] were investigated.

Results

A total of 115 608 patients (60.6% men) were hospitalized for a first AMI during the study period. Mortality at 28 days was reduced annually by 3.8% overall and by 6.7%, 4.1% and 2.6% in patients aged 25–64, 65–84 and ≥85 years, respectively (all Ptrend < 0.001). In addition, 1-year all-cause mortality was reduced annually by 2.0% overall (Ptrend < 0.001) and by 3.7% (Ptrend = 0.02), 2.5% (Ptrend < 0.001) and 1.1% (Ptrend < 0.001) in patients aged 25–64, 65–84 and ≥85 years, respectively. Furthermore, 1-year CVD mortality was reduced overall by 6.2% annually; a reduction was observed in all age groups. Finally, 1-year non-CVD mortality increased annually overall by 3.9% due to an increase in patients aged ≥65 years.

Conclusion

Mortaity at 28 days after the first AMI declinedin Norway between 2001 and 2009 in both men and women and in all age groups. All-cause mortality at 1 year also declined both in men and women due to decreases in CVD mortality rates, whilst non-CVD mortality rates increased amongst patients ≥65 years of age.

Ancillary