Conflict of interest: None identified.
Central nervous system tuberculosis: A disease from Papua New Guinea in North Queensland
Article first published online: 10 MAR 2013
© 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Journal of Paediatrics and Child Health
Volume 49, Issue 3, pages E193–E198, March 2013
How to Cite
Ting, P. L. and Norton, R. (2013), Central nervous system tuberculosis: A disease from Papua New Guinea in North Queensland. Journal of Paediatrics and Child Health, 49: E193–E198. doi: 10.1111/jpc.12107
- Issue published online: 10 MAR 2013
- Article first published online: 10 MAR 2013
- Manuscript Accepted: 4 MAY 2012
- central nervous system tuberculosis;
- multidrug-resistant tuberculosis;
- North Queensland;
- Papua New Guinea;
To describe cases of confirmed central nervous system (CNS) tuberculosis seen at the major tertiary referral centre of North Queensland over a 10-year period.
This is a retrospective case series-based study of all cases of proven Mycobacterium tuberculosis infection of the CNS presenting to a major tertiary referral centre of North Queensland between 2000 and 2010.
Five cases of confirmed CNS tuberculosis were identified over the 10-year period with two deaths. All were from Papua New Guinea with a mean age of 7 years. Imaging and early microbiological diagnosis was critical in making the diagnosis. HIV infection was not a contributing factor. Multidrug resistance was inferred or confirmed in two cases.
CNS tuberculosis is a disease being increasingly seen in North Queensland among children from Papua New Guinea. Anticipation of multidrug resistance is important in the immediate management of suspected cases.