Conflict of interest: none.
Enteroviral myocarditis in neonates
Article first published online: 27 MAY 2013
© 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Journal of Paediatrics and Child Health
Volume 49, Issue 9, pages E451–E454, September 2013
How to Cite
Schlapbach, L. J., Ersch, J., Balmer, C., Prêtre, R., Tomaske, M., Caduff, R., Morwood, J., Provenzano, S. and Stocker, C. (2013), Enteroviral myocarditis in neonates. Journal of Paediatrics and Child Health, 49: E451–E454. doi: 10.1111/jpc.12248
- Issue published online: 5 SEP 2013
- Article first published online: 27 MAY 2013
- Manuscript Accepted: 19 NOV 2012
- extracorporeal membrane oxygenation;
Enteroviruses are a leading cause of viral infections in children. While most enteroviral infections are mild and self-limiting, severe disease such as a viral sepsis syndrome, myocarditis, hepatitis and meningoencephalitis may occur. We present two cases of neonatal enteroviral myocarditis. Cardiorespiratory failure occurred in both cases, and severe shock refractory to conventional treatment required support with extracorporeal membrane oxygenation (ECMO). One child with coxsackievirus B3 myocarditis failed to recover and died after 3 weeks on ECMO, while one child could be decannulated successfully after 9 days of ECMO and recovered completely subsequently. In conclusion, neonatal myocarditis has a very high mortality, and ECMO should be considered early in neonates with rapid clinical and echocardiographic deterioration despite adequate inotropic support.