Financial Support: DGT is supported by a National Health and Medical Research Council Clinical Research Fellowship (Grant ID 491286) and the Victorian Government Operational Infrastructure Support Program. PGD is supported by a National Health and Medical Research Council Program Grant (Grant ID 606789) and a National Health and Medical Research Council Practitioner Fellowship (Grant ID 556600).
Dräger VN500's oscillatory performance has a frequency-dependent threshold
Article first published online: 9 OCT 2013
© 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Journal of Paediatrics and Child Health
Volume 50, Issue 1, pages 27–31, January 2014
How to Cite
John, J., Harcourt, E. R., Davis, P. G. and Tingay, D. G. (2014), Dräger VN500's oscillatory performance has a frequency-dependent threshold. Journal of Paediatrics and Child Health, 50: 27–31. doi: 10.1111/jpc.12398
Competing interests: The authors have no competing interests to declare.
Contributor's Statements: All authors made substantial contributions to conception and design, data acquisition, analysis, and interpretation. All authors were involved in the drafting and critical review of the submitted manuscript and approve of the manuscript in current form, with Drs John and Tingay writing the first draft.
- Issue published online: 7 JAN 2014
- Article first published online: 9 OCT 2013
- Manuscript Accepted: 6 JUN 2013
- National Health and Medical Research Council Clinical Research Fellowship. Grant Number: 491286
- National Health and Medical Research Council Program Grant. Grant Number: 606789
- National Health and Medical Research Council Practitioner Fellowship. Grant Number: 556600
- high-frequency oscillatory ventilation;
- mechanical ventilation;
The aim of this study is to compare the high-frequency pressure amplitude (oscillatory change in pressure (ΔP)) and tidal volume (high-frequency tidal volume at the airway opening (VTHF)) delivered by the Dräger VN500 (Drägerwerk Ag & Co., Lübeck, Germany) and the Sensormedics 3100 (SM3100; CareFusion, San Diego, CA, USA) through a range of oscillatory frequencies.
In this benchtop study, high-frequency oscillations were applied to an infant test lung at unrestricted set amplitudes. Pressure and flow were measured as a function of frequency, incremented by 1 Hz from 5 to 15 Hz. Measurements were repeated for a range of ventilator settings, and lung resistive and compliance states.
The VN500, but not the SM3100, demonstrated an exponential decrease in airway opening ΔP as frequency increased. The difference between the SM3100- and VN500-delivered VTHF became greater with each frequency increment. At 15 Hz, VN500 VTHF was 49% of SM3100 VTHF.
The VN500 demonstrates a frequency-related reduction in ΔP not observed in the SM3100. Clinicians need to be aware of these differences in performance characteristics.