Conflict of interest: None.
Prevention and treatment of intraluminal catheter thrombosis in children hospitalised in a paediatric intensive care unit
Article first published online: 18 OCT 2013
© 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Journal of Paediatrics and Child Health
Volume 50, Issue 1, pages 40–46, January 2014
How to Cite
de Lorenzo-Pinto, A., Sánchez-Galindo, A. C., Manrique-Rodríguez, S., Fernández-Llamazares, C. M., Fernández-Lafever, S. N., San-Prudencio, M. G., Cortejoso, L. and Sanjurjo-Sáez, M. (2014), Prevention and treatment of intraluminal catheter thrombosis in children hospitalised in a paediatric intensive care unit. Journal of Paediatrics and Child Health, 50: 40–46. doi: 10.1111/jpc.12404
- Issue published online: 7 JAN 2014
- Article first published online: 18 OCT 2013
- intensive care units;
- thrombolytic therapy
The aim of the study was to develop and implement a protocol for the prevention and treatment of catheter related intraluminal thrombosis in a paediatric intensive care unit
A computerised search was carried out on MEDLINE, through PubMed, using the medical subject heading ‘central venous catheter’, ‘central venous access device’, ‘central venous line’ associated with ‘occlusion’, ‘obstruction’, ‘catheter-related thrombosis’, ‘critically ill patients’ and ‘thrombolytic therapy’. References of reviewed articles were also searched for relevant titles as well as non-randomised controlled trials and series of cases when no information of higher level of evidence was available.
With the information gathered, a protocol for the prevention and treatment of catheter related intraluminal thrombosis was elaborated and those recommendations that best suit our environment were included. They were agreed upon by a broad panel of professionals working in the Pediatric Intensive Care Unit and the Pharmacy Department.
Due to the variety of options available for the pharmacotherapeutic management of intraluminal catheter thrombosis, one measure to improve the quality of the therapy and to diminish the variability in the prescription could be the implementation of a protocol as described in this paper.