Invasive group A streptococcal infection in the Northern Territory, Australia: Case report and review of the literature

Authors

  • Bianca Middleton,

    Corresponding author
    1. The Royal Children's Hospital, Melbourne, Victoria, Australia
    • Correspondence: Dr Bianca Middleton, The Royal Children's Hospital, Flemington Road, Parkville, Vic. 3052, Australia. Fax: +613 93454751; email: bianca.middleton@rch.org.au

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  • Peter Morris,

    1. Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia
    2. Department of Paediatrics, Royal Darwin Hospital, Darwin, Northern Territory, Australia
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  • Jonathan Carapetis

    1. Telethon Institute for Child Health Research, University of Western Australia
    2. Princess Margaret Hospital for Children, Perth, Western Australia, Australia
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  • Conflict of interest: None identified.

Abstract

The increasing incidence of invasive group A streptococcus has been well documented in the temperate climates of North America, Europe and the United Kingdom. Studies also suggest that there are high rates of invasive group A streptococcus infection within the indigenous population of Northern Australia. This review article presents the case of infant Aboriginal twins with invasive group A streptococcal infection complicated by streptococcal toxic shock syndrome, highlighting both the severity and high transmissibility of invasive group A streptococcal disease. We review the epidemiology of group A streptococcal infection and suggest a potential role for chemoprophylaxis of household contacts to reduce the burden of disease within the indigenous population of Northern Australia.

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