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jpi12059-sup-0001-FigS1.tifimage/tif5133KFigure S1. Infarct size expressed as % of the area at risk. Melatonin (50 μm) administration during the initial 30 min of reperfusion reduced infarct size produced by 30 min of regional ischemia and 120 minutes of reperfusion from 30.0 ± 2.2 to 7.1 ± 1.3 in Wistar Kyoto rats (WKY), from 31.6 ± 4.0 to 9.8 ± 2.6 in FFR, and from 32.7 ± 2.9 to 12.8 ± 2.0 in SHR (all values are mean percentage of the area at risk ± SEM, n = 6; *** P < 0.001 melatonin-treated versus vehicle-treated hearts).

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