Journal of Pineal Research

Cover image for Journal of Pineal Research

August 1990

Volume 9, Issue 1

Pages 1–94

    1. Circadian Rhythms of Human Pineal Melatonin, Related Indoles, and Beta Adrenoreceptors: Post-Mortem Evaluation (pages 1–11)

      G. F. Oxenkrug, G. F. Anderson, L. Dragovic, M. Blaivas and P. Riederer

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00688.x

    2. Light Suppression of Melatonin in the Squirrel Monkey (Saimiri sciureus) (pages 13–19)

      Tana M. Hoban, Alfred. J. Lewy and Charles A. Fuller

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00689.x

    3. Alpha-1 Adrenoceptor Involvement in the Control of Melatonin Secretion in the Golden Hamster (pages 21–28)

      Bojidar Stankov, Valeria Lucini, Marco Mariani, Francesco Scaglione, Germana Demartini and Franco Fraschini

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00690.x

    4. Choline Acetyltransferase in Bovine Pineal Gland (pages 29–38)

      P. Phansuwan-Pujito, P. Govitrapong and M. Ebadi

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00691.x

    5. Saliva and serum samples were collected from eight healthy volunteers every two hours during a 26-hour period. Melatonin concentrations were measured by radioimmunoassay after chloroform extraction using radioiodinated melatonin as a tracer. Five of the subjects had high serum melatonin levels at night (peak levels higher than 75 pg/ml); in three subjects the highest serum melatonin concentration was 20-40 pg/ml. All subjects had low levels (<10 pg/ml) during the day. The correlations between salivary and serum levels were calculated. The regression line y =0.33×+ 3.7 pg/ml, r= 0.95, P <0.001, was obtained for all detectable value pairs (n= 73). The regression and correlation coefficients were almost equal for the peak values of melatonin and during the rising and descending phases of the secretion patterns. However, no significant correlation was found between low daytime salivary and serum concentrations when calculated separately. In the five high-secretors the melatonin levels in saliva reflected reliably the changes in serum, but in the three low-secretors the correlation between salivary and serum melatonin was not significant. The proportion of melatonin found in saliva decreased with increasing serum melatonin levels. Circadian rhythm parameters were estimated by single cosinor analysis. The acrophases did not differ significantly within a subject in the concomitant measurements of serum and salivary melatonin. The measurements of salivary melatonin levels seem valid for studies on melatonin rhythms, but the melatonin concentrations measured in saliva do not always consistently reflect the absolute concentrations in blood. (pages 39–50)

      Maija-Liisa Laakso, Tarja Porkka-Heiskanen, Aino Alila, Dag Stenberg and Gunnar Johansson

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00692.x

    6. Time-Dependent Effect of Melatonin on Actin mRNA Levels and Incorporation of 35S-Methionine Into Actin and Proteins by the Rat Hypothalamus (pages 51–63)

      Juan Iovanna, Nelson Dusetti, Belen Cadenas and Daniel P. Cardinali

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00693.x

    7. Thymidine Incorporation by Chick Pineal Glands as Studied by Pulse-Labelling In Vitro (pages 85–94)

      S. D. Wainwright and Lillian K. Wainwright

      Version of Record online: 30 JAN 2007 | DOI: 10.1111/j.1600-079X.1990.tb00696.x