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Chemical Biology & Drug Design

Cover image for Vol. 67 Issue 1

January 2006

Volume 67, Issue 1

Pages 1–98

  1. Editorial

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
    1. You have free access to this content
      Chemical Biology & Drug Design: Inaugural issue! (page 1)

      Tomi K. Sawyer

      Version of Record online: 8 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00321.x

  2. Perspectives

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
    1. You have free access to this content
      Overcoming Roadblocks in Lead Optimization: A Thermodynamic Perspective (pages 2–4)

      Adam J Ruben, Yoshiaki Kiso and Ernesto Freire

      Version of Record online: 8 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00314.x

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  3. Reviews

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
    1. You have free access to this content
    2. You have free access to this content
  4. Research Articles

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
    1. You have free access to this content
      The Role of Water in Computational and Experimental Derivation of Binding Thermodynamics in SH2 Domains (pages 38–45)

      Sebastien Geroult, Satpal Virdee and Gabriel Waksman

      Version of Record online: 8 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00315.x

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      Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds (pages 46–57)

      David Dalgarno, Thilo Stehle, Surinder Narula, Pierre Schelling, Marie Rose van Schravendijk, Susan Adams, Lawrence Andrade, Jeff Keats, Mary Ram, Lei Jin, Trudy Grossman, Ian MacNeil, Chester Metcalf III, William Shakespeare, Yihan Wang, Terry Keenan, Raji Sundaramoorthi, Regine Bohacek, Manfred Weigele and Tomi Sawyer

      Version of Record online: 8 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00316.x

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      Structure-based Optimization of MurF Inhibitors (pages 58–65)

      Geoffrey F. Stamper, Kenton L. Longenecker, Elizabeth H. Fry, Clarissa G. Jakob, Alan S. Florjancic, Yu-Gui Gu, David D. Anderson, Curt S. Cooper, Tianyuan Zhang, Richard F. Clark, Yingna Cia, Candace L. Black-Schaefer, J. Owen McCall, Claude G. Lerner, Philip J. Hajduk, Bruce A. Beutel and Vincent S. Stoll

      Version of Record online: 16 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00317.x

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      Cellular Analysis of Disorazole C1 and Structure–Activity Relationship of Analogs of the Natural Product (pages 66–73)

      Peter Wipf, Thomas H. Graham, Andreas Vogt, Rachel P. Sikorski, Alexander P. Ducruet and John S. Lazo

      Version of Record online: 8 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00313.x

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      The Discovery of Small Molecule Inhibitors of Neutral Endopeptidase. Structure–Activity Studies on Functionalized Glutaramides (pages 74–77)

      Graham N. Maw, Alan Stobie, Simon Planken, David C. Pryde, Vivienne Sanderson, Michelle Y. Platts, Martin Corless, Peter Stacey, Christopher Wayman, Piet Van Der Graaf, Christopher Kohl, Sara Coggon and Kevin Beaumont

      Version of Record online: 21 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00320.x

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      Stability of Gold Nanoparticle-Bound DNA toward Biological, Physical, and Chemical Agents (pages 78–82)

      Gang Han, Craig T. Martin and Vincent M. Rotello

      Version of Record online: 21 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00324.x

  5. R & D Technology Forum

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
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      Use of an Induced Fit Receptor Structure in Virtual Screening (pages 83–84)

      Woody Sherman, Hege S. Beard and Ramy Farid

      Version of Record online: 8 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00327.x

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      A Chemogenomic Approach to Discovering Target-Selective Drugs (pages 85–86)

      William P. Janzen and C. Nicholas Hodge

      Version of Record online: 21 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00325.x

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      Biochemical Microarrays for Studying Chemical Biology Interaction: DiscoveryDotTM Technology (pages 87–88)

      Kurumi Y. Horiuchi, Yuan Wang and Haiching Ma

      Version of Record online: 21 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00326.x

  6. Who's Who in Chemical Biology & Drug Design

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
    1. You have free access to this content
  7. Calendar of Events

    1. Top of page
    2. Editorial
    3. Perspectives
    4. Reviews
    5. Research Articles
    6. R & D Technology Forum
    7. Who's Who in Chemical Biology & Drug Design
    8. Calendar of Events
    1. You have free access to this content
      Calendar of Events (pages 96–98)

      Version of Record online: 21 DEC 2005 | DOI: 10.1111/j.1747-0285.2005.00334.x

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