Both authors contributed equally to this work.
Polyphosphate binds to human von Willebrand factor in vivo and modulates its interaction with glycoprotein Ib
Article first published online: 30 OCT 2012
© 2012 International Society on Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis
Volume 10, Issue 11, pages 2315–2323, November 2012
How to Cite
MONTILLA, M., HERNÁNDEZ-RUIZ, L., GARCÍA-COZAR, F. J., ALVAREZ-LADERAS, I., RODRÍGUEZ-MARTORELL, J. and RUIZ, F. A. (2012), Polyphosphate binds to human von Willebrand factor in vivo and modulates its interaction with glycoprotein Ib. Journal of Thrombosis and Haemostasis, 10: 2315–2323. doi: 10.1111/jth.12004
- Issue published online: 30 OCT 2012
- Article first published online: 30 OCT 2012
- Accepted manuscript online: 24 SEP 2012 09:31PM EST
- Received 9 March 2012, accepted 13 September 2012
Figure S1. PolyP in platelet alpha granules.
Figure S2. Specific depletion of polyP affects von Willebrand Factor ristocetin cofactor activity.
Figure S3. PolyP depletion does not affect normal von Willebrand Factor multimer distribution.
Figure S4. PolyP levels does not affect normal von Willebrand Factor collagen binding.
Table S1. Identification of proteins in bands sliced from SDS-PAGE after immuno-precipitation of normal human platelets with anti-von Willebrand factor antibody (shown in Fig. 2A).
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