Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation

Authors

  • A. L. VANDEN HOEK,

    1. Research and Development Department, Canadian Blood Services
    2. University of British Columbia (UBC)/Centre for Blood Research
    3. Department of Pathology and Laboratory Medicine, UBC
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  • K. TALBOT,

    1. Research and Development Department, Canadian Blood Services
    2. University of British Columbia (UBC)/Centre for Blood Research
    3. Department of Pathology and Laboratory Medicine, UBC
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  • I. S. R. CARTER,

    1. University of British Columbia (UBC)/Centre for Blood Research
    2. Department of Genetics, UBC
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  • L. VICKARS,

    1. University of British Columbia (UBC)/Centre for Blood Research
    2. Hematology, St Paul’s Hospital, Providence Health Care
    3. Department of Experimental Medicine, UBC
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  • C. J. CARTER,

    1. University of British Columbia (UBC)/Centre for Blood Research
    2. Department of Pathology and Laboratory Medicine, UBC
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  • S. C. JACKSON,

    1. University of British Columbia (UBC)/Centre for Blood Research
    2. Hematology, St Paul’s Hospital, Providence Health Care
    3. Department of Experimental Medicine, UBC
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  • R. T. A. MacGILLIVRAY,

    1. University of British Columbia (UBC)/Centre for Blood Research
    2. Department of Biochemistry and Molecular Biology, UBC, Vancouver, British Columbia, Canada
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  • E. L. G. PRYZDIAL

    1. Research and Development Department, Canadian Blood Services
    2. University of British Columbia (UBC)/Centre for Blood Research
    3. Department of Pathology and Laboratory Medicine, UBC
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Edward L. G. Pryzdial, University of British Columbia/Centre for Blood Research, 2350 Health Science Mall, Vancouver, British Columbia, Canada, V6T 1Z3.
Tel.: +1 604 822 3823; fax: +1 604 822 7185.
E-mail: ed.pryzdial@blood.ca

Abstract

Vanden Hoek AL, Talbot K, Carter ISR, Vickars L, Carter CJ, Jackson SC, MacGillivray RTA, Pryzdial ELG. Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation. J Thromb Haemost 2012; 10: 2613–5.

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