These authors contributed equally to this work.
LETTERS TO THE EDITOR
Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose
Version of Record online: 12 DEC 2012
© 2012 International Society on Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis
Volume 10, Issue 12, pages 2607–2609, December 2012
How to Cite
ARMSTRONG, P. C. J., HU, H., RIVERA, J., RIGBY, S., CHEN, Y.-C., HOWDEN, B. P., GARDINER, E. and PETER, K. (2012), Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose. Journal of Thrombosis and Haemostasis, 10: 2607–2609. doi: 10.1111/jth.12022
- Issue online: 12 DEC 2012
- Version of Record online: 12 DEC 2012
- Accepted manuscript online: 5 OCT 2012 11:38AM EST
- Received 5 August 2012, accepted 23 September 2012
Fig. S1. No inhibition by 5E3 mAb (5–50 μg mL−1) of ADP (20 μM)- induced P-selectin expression, a marker of platelet activation, as measured by flow cytometry.
Fig. S2. 5E3 mAb (50 μg mL−1) and Bimosiamose (1 mM) directly prevent SSL5 (10 μg mL−1)-binding to platelets.
Fig. S3. Representative lung sections from mice administered SSL5 (4 μg g−1; i.v.) intravenously.
Data S1. Methods and Materials.
|JTH_12022_sm_FigS1-S3.pdf||177K||Supporting info item|
|JTH_12022_sm_Methods-and-Materials.doc||54K||Supporting info item|
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