ORIGINAL ARTICLE

Platelets express and release osteocalcin and co-localize in human calcified atherosclerotic plaques

  1. C. FORESTA1,
  2. G. STRAPAZZON1,2,
  3. L. DE TONI1,
  4. F. FABRIS3,
  5. F. GREGO4,
  6. G. GEROSA5,
  7. S. VETTORE3,
  8. A. GAROLLA1

Article first published online: 7 FEB 2013

DOI: 10.1111/jth.12088

Issue

Journal of Thrombosis and Haemostasis

Journal of Thrombosis and Haemostasis

Volume 11, Issue 2, pages 357–365, February 2013

Additional Information

How to Cite

FORESTA, C., STRAPAZZON, G., DE TONI, L., FABRIS, F., GREGO, F., GEROSA, G., VETTORE, S. and GAROLLA, A. (2013), Platelets express and release osteocalcin and co-localize in human calcified atherosclerotic plaques. Journal of Thrombosis and Haemostasis, 11: 357–365. doi: 10.1111/jth.12088

Author Information

  1. 1

    Section of Clinical Pathology and Human Reproduction Pathology Service, Department of Histology, Microbiology and Medical Biotechnologies, University of Padova

  2. 2

    EURAC Institute of Mountain Emergency Medicine, Bozen/Bolzano

  3. 3

    Department of Medicine, University of Padova Medical School, Padova

  4. 4

    Department of Cardiac, Thoracic and Vascular Sciences, University of Padova

  5. 5

    Department of Cardiac, Thoracic and Vascular Sciences, Section of Vascular and Endovascular Surgery, University of Padua, Padua, Italy

* Carlo Foresta, Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Via Gabelli 63, 35121 Padova, Italy. Tel.: +39 49 8218517; fax: +39 49 8218520. E-mail: carlo.foresta@unipd.it

Publication History

  1. Issue published online: 7 FEB 2013
  2. Article first published online: 7 FEB 2013
  3. Accepted manuscript online: 3 DEC 2012 12:02PM EST
  4. Received 9 May 2012, accepted 13 November 2012

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Figure S1. Evaluation of binding of osteocalcin on cell surface of resting platelets.

Figure S2. Localization pattern of osteocalcin in resting and activated platelets and mepacrine assay.

Figure S3. Osteocalcin in the atherosclerotic carotid artery of patients undergoing edoarterectomy.

Figure S4. Expression of osteocalcin in normal carotid artery and skeletal muscle.

Figure S5. Expression of osteocalcin in normal carotid artery.

FilenameFormatSizeDescription
jth12088_sm_FigS1.pdf555KSupporting info item
jth12088_sm_FigS2.pdf46KSupporting info item
jth12088_sm_FigS3.pdf166KSupporting info item
jth12088_sm_FigS4.pdf787KSupporting info item
jth12088_sm_FigS5.pdf246KSupporting info item
jth12088_sm_Supplementary-material.doc45KSupporting info item

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