Article first published online: 30 JUN 2013
© 2013 International Society on Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis
Special Issue: State of the Art 2013
Volume 11, Issue Supplement s1, pages 67–74, June 2013
How to Cite
Synthetic microvessels. J Thromb Haemost 2013; 11 (Suppl. 1): 67–74., .
- Issue published online: 30 JUN 2013
- Article first published online: 30 JUN 2013
- Manuscript Accepted: 25 MAR 2013
- Manuscript Received: 1 MAR 2013
- von Willebrand factor
The microvasculature is an immense organ that defines the environmental conditions within tissues in both health and disease, and is vital for the proper functions of all tissues. Here, we describe existing tools to study vascular cell function and our work using one platform of in vitro microvessels, which we employed to study vessel structure and remodeling, endothelial barrier function, angiogenesis, interactions between endothelial cells and perivascular cells, interactions between blood cells and the endothelium, and microvascular thrombosis. We also briefly discuss the potential future applications of these platforms in biology and medicine.