Asymptomatic Schistosoma haematobium Infection in a Traveler With Negative Urine Microscopy and Late Seroconversion Presumably Linked to Artemisinin


Corresponding Author: José Ramón Yuste, MD, PhD, Division of Infectious Diseases, Department of Internal Medicine, Clínica Universidad de Navarra, Pamplona, Spain. E-mail:


We describe a Schistosoma haematobium infection with asymptomatic eosinophilia, persistently negative urine microscopy, and late seroconversion (7.5 months) in a traveler returning from Mali. After initial negative parasitological tests, travel history led to diagnostic cystoscopy, allowing final diagnosis with urine microscopy after the bladder biopsy. The patient was successfully treated with praziquantel. Difficulties in making the diagnosis of schistosomiasis in asymptomatic returning travelers are discussed; we propose a trial treatment in these cases.