Major West Indies MRSA Clones in Human Beings: Do They Travel With Their Hosts?

Authors

  • Tomasz Chroboczek MD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Sandrine Boisset PhD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Jean-Philippe Rasigade MD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Helene Meugnier PhD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Patrick E. Akpaka MD,

    1. Pathology/Microbiology Unit, Department of Para-Clinical Sciences, The University of the West Indies, St. Augustine, Trinidad & Tobago
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  • Alison Nicholson MD,

    1. Department of Microbiology, The University Hospital of the West Indies, Kingston 7, Jamaica
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  • Muriel Nicolas MD,

    1. Department of Microbiology, University Hospital of Pointe-à-Pître, Guadeloupe, France
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  • Claude Olive MD,

    1. Department of Microbiology, University Hospital of Fort-de-France, Martinique, France
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  • Michele Bes PhD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • François Vandenesch MD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Frederic Laurent PharmD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Jerome Etienne MD,

    1. French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
    2. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
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  • Anne Tristan PharmD

    Corresponding author
    1. INSERM U851, Faculté de Médecine Lyon Est, University of Lyon, Lyon, France
    • French National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France
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Corresponding Author: Anne Tristan, PharmD, Centre National de Référence des Staphylocoques, Centre de Biologie et Pathologie Est—CBPE, Groupement Hospitalier Est, 59 boulevard Pinel, F-69677 Bron, France. E-mail: anne.tristan@univ-lyon1.fr

Abstract

Background

Descriptions of the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) have seldom been produced in the Caribbean, which is a major tourism destination.

Materials and Methods

Using DNA microarrays and spa typing, we characterized 85 MRSA isolates from human skin and soft-tissue infections from five different islands.

Results

In the French West Indies (n = 72), the most frequently isolated clones were the same clones that are specifically isolated from mainland France [Lyon (n = 35) and Geraldine (n = 11) clones], whereas the clones that were most frequently isolated from the other islands (n = 13) corresponded with clones that have a worldwide endemic spread [Vienna/Hungarian/Brazilian (n = 5), Panton Valentine leukocidin-positive USA300 (n = 4), New York/Japan (n = 2), and pediatric (n = 1) clones].

Conclusion

The distribution of the major MRSA clones in the French (Guadeloupe and Martinique) and non-French West Indies (Jamaica, Trinidad, and Tobago) is different, and the clones most closely resemble those found in the home countries of the travelers who visit the islands most frequently. The distribution might be affected by tourist migration, which is specific to each island.

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