Apropos “Point-of-Care Syndrome-Based, Rapid Diagnosis of Infections on Commercial Ships”


To the Editor-in-Chief

We compliment the team of investigators from Marseille, France, for introducing infectious diseases point-of-care (POC) syndrome-based diagnostics on board a freight liner and a cruise ship[1] and believe that similar testing should be incorporated for coronary and other cardiac events. A rapid and accurate diagnosis of acute myocardial infarction (AMI) is crucial for saving lives. Cardiovascular emergencies, such as acute coronary syndrome and heart failure, are not uncommon on cruise ships. They are often serious, requiring hospital triage and cruise liners have been asked to establish mechanisms for prompt consultation for coronary revascularization.[2]

Recently, a rapid, automatic POC biosensing system for simultaneous quantification of four cardiac markers has been offered in a sensing operation with a reliable and user-friendly assay format. Employing an automatic four cardiac marker sensing system with a 2 × 2.5 cm2 sensing chip, the POC assay requires only 200 μL of plasma sample with an assay time of 15 minutes.[3] Furthermore, eight observational studies have collectively demonstrated an added diagnostic value of the prehospital POC test in relation to AMI while the prehospital POC test for cardiac markers would be significant in non-ST segment elevation myocardial infarction care in the near future.[4]

In conclusion, incorporation of POC assays for cardiac markers[3, 4] in the infectious diseases POC syndrome-based diagnostics[1] would be useful for those with different cardiac disorders[2] while on board any freight liner or cruise ship.