All work was performed at the Livestock Veterinary Services Hospital and the Clinical Pathology Laboratory at the Colorado State University Veterinary Teaching Hospital, Fort Collins, CO. A poster presentation of this project was given at the 2012 American College of Veterinary Internal Medicine Forum, New Orleans, LA and at the 2012 Colorado State University College of Veterinary Medicine and Biomedical Sciences Research Day, Fort Collins, CO
Evaluation of Four Point-Of-Care Glucose Meters in Alpacas
Article first published online: 4 JUN 2013
Copyright © 2013 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 27, Issue 4, pages 990–995, July/August 2013
How to Cite
Beemer, O., Byers, S. and Bohn, A. (2013), Evaluation of Four Point-Of-Care Glucose Meters in Alpacas. Journal of Veterinary Internal Medicine, 27: 990–995. doi: 10.1111/jvim.12115
- Issue published online: 15 JUL 2013
- Article first published online: 4 JUN 2013
- Manuscript Accepted: 18 APR 2013
- Manuscript Revised: 16 APR 2013
- Manuscript Received: 21 MAY 2012
- Colorado State University Center
- PVM Student Research Grant Program
Hospitalized alpacas are often hyperglycemic requiring frequent blood glucose testing.
To compare the performance of 4 brands of glucometers with a laboratory-based analyzer (LCA) over a range of glucose concentrations in alpacas.
Four healthy male alpacas.
A 2-treatment cross-over study was utilized. The alpacas were given 0.4 U/kg of regular insulin intravenously and then 500 mg/kg of dextrose intravenously with a 1 week washout period between treatments. Blood samples were collected from 10 minutes before until 6 hours after drug administration. Glucose concentrations were measured in whole blood and plasma samples on 4 glucometers, and serum glucose was measured on an LCA.
Glucometer performance varied depending on whether glucose concentrations were measured in plasma or whole blood. Based on error grid analysis, the Precision Xtra and One Touch Ultra 2 glucometers were clinically acceptable for testing whole blood samples, whereas the Accu-Chek Aviva and Nova StatStrip Xpress glucometers were clinically acceptable for testing plasma samples in comparison with serum glucose concentrations determined by the LCA. All glucometers had systematic and proportional biases that varied based on sample type.
Conclusions and Clinical Importance
Human-based glucometers in alpacas should be used cautiously, particularly at higher blood glucose concentrations. The blood sample type (plasma or whole blood) can alter meter performance when compared with serum glucose concentrations and potentially lead to errors in clinical decisions.