Part of this work was presented at the Australian College of Veterinary Scientists science week, Gold Coast, Queensland, Australia, June 30–July 2 2011
Clinical Findings and Survival in Cats Naturally Infected with Feline Immunodeficiency Virus
Version of Record online: 4 JUN 2013
Copyright © 2013 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 27, Issue 4, pages 798–805, July/August 2013
How to Cite
Liem, B.P., Dhand, N.K., Pepper, A.E., Barrs, V.R. and Beatty, J.A. (2013), Clinical Findings and Survival in Cats Naturally Infected with Feline Immunodeficiency Virus. Journal of Veterinary Internal Medicine, 27: 798–805. doi: 10.1111/jvim.12120
- Issue online: 15 JUL 2013
- Version of Record online: 4 JUN 2013
- Manuscript Accepted: 25 APR 2013
- Manuscript Revised: 18 MAR 2013
- Manuscript Received: 10 AUG 2012
Vol. 27, Issue 5, 1288, Version of Record online: 13 SEP 2013
- Clinicopathological findings;
- Feline immunodeficiency virus;
The clinical course and outcome of natural feline immunodeficiency virus (FIV) infection are variable and incompletely understood. Assigning clinical relevance to FIV infection in individual cats represents a considerable clinical challenge.
To compare signalment, hematologic and biochemical data, major clinical problem, and survival among client-owned, FIV-infected, and uninfected domestic cats.
Client-owned, domestic cats tested for FIV (n = 520).
Retrospective, case control study. Logistic regression analyses were conducted to identify risk factors for FIV infection and to compare hematologic and biochemical data between cases and controls, after adjusting for potential confounders. Survival times were compared using Kaplan–Meier curves.
The prevalence of FIV infection was 14.6%. Mixed breed, male sex, and older age were risk factors for FIV infection. Hematologic abnormalities, biochemical abnormalities or both were common in both FIV-infected and uninfected cats. Lymphoid malignancies were slightly more common in FIV-infected than uninfected cats. Survival of FIV-infected cats was not significantly different from that of uninfected cats.
Conclusions and Clinical Importance
Multiple hematologic and biochemical abnormalities are common in old, sick cats regardless of their FIV status. Their presence should not be assumed to indicate clinical progression of FIV infection. A negative effect of FIV on survival was not apparent in this study.