• Open Access

Clinical Findings and Survival in Cats Naturally Infected with Feline Immunodeficiency Virus

Authors

Errata

This article is corrected by:

  1. Errata: Erratum Volume 27, Issue 5, 1288, Article first published online: 13 September 2013

  • Part of this work was presented at the Australian College of Veterinary Scientists science week, Gold Coast, Queensland, Australia, June 30–July 2 2011

Corresponding author: J. Beatty, Valentine Charlton Cat Centre, Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia, e-mail: julia.beatty@sydney.edu.au.

Abstract

Background

The clinical course and outcome of natural feline immunodeficiency virus (FIV) infection are variable and incompletely understood. Assigning clinical relevance to FIV infection in individual cats represents a considerable clinical challenge.

Objective

To compare signalment, hematologic and biochemical data, major clinical problem, and survival among client-owned, FIV-infected, and uninfected domestic cats.

Animals

Client-owned, domestic cats tested for FIV (n = 520).

Methods

Retrospective, case control study. Logistic regression analyses were conducted to identify risk factors for FIV infection and to compare hematologic and biochemical data between cases and controls, after adjusting for potential confounders. Survival times were compared using Kaplan–Meier curves.

Results

The prevalence of FIV infection was 14.6%. Mixed breed, male sex, and older age were risk factors for FIV infection. Hematologic abnormalities, biochemical abnormalities or both were common in both FIV-infected and uninfected cats. Lymphoid malignancies were slightly more common in FIV-infected than uninfected cats. Survival of FIV-infected cats was not significantly different from that of uninfected cats.

Conclusions and Clinical Importance

Multiple hematologic and biochemical abnormalities are common in old, sick cats regardless of their FIV status. Their presence should not be assumed to indicate clinical progression of FIV infection. A negative effect of FIV on survival was not apparent in this study.

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