Parts of the study were presented at the annual ECVN/ESVN meeting in Munich 2005. The work was done at the University of Veterinary Medicine, Hannover and the School of Medicine, Hannover, Germany
Morphometric Parameters of Peripheral Nerves in Calves Correlated with Conduction Velocity
Version of Record online: 13 JAN 2014
Copyright © 2014 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 28, Issue 2, pages 646–655, March/April 2014
How to Cite
Schenk, H.C., Haastert-Talini, K., Jungnickel, J., Grothe, C., Meyer, H., Rehage, J., Fehr, M., Bokemeyer, J., Rohn, C. and Tipold, A. (2014), Morphometric Parameters of Peripheral Nerves in Calves Correlated with Conduction Velocity. Journal of Veterinary Internal Medicine, 28: 646–655. doi: 10.1111/jvim.12271
- Issue online: 15 MAR 2014
- Version of Record online: 13 JAN 2014
- Manuscript Accepted: 6 NOV 2013
- Manuscript Revised: 21 SEP 2013
- Manuscript Received: 14 DEC 2012
- Precocial species
Peripheral nerve injuries are the most frequent neurologic disorder in cattle. So far, no physiologic values have been established for the motor nerve conduction velocity (mNCV) in this precocial species.
The electrophysiologic and morphometric reference values of peripheral nerves in calves were determined. It was hypothesized that these parameters would correlate to the high degree of maturity in the first days of life in this species compared to other species.
Twenty-six healthy calves were used in this study.
The mNCV of the radial and the sciatic/common peroneal nerve was measured in all 26 calves. Nerve biopsies from a group of 6 calves were taken to correlate the obtained electrophysiologic data with morphological parameters.
The mean mNCV of the radial nerve was 48.3 ± 10.6 m/s, whereas the mean mNCV of the sciatic/peroneal nerve was with 83.8 ± 5.9 m/s significantly faster (P < .0001). The average fiber diameter was 8.40 ± 2.80 μm (range, 1.98–17.90 μm) and the average g-ratio was 0.61 ± 0.04 SD.
Conclusion and Clinical Importance
The established reference values for mNCV in calves correlate well with the evaluated morphometric parameters. Attributable to their comparably fast mNCV and high fiber diameters, juvenile calves appear to be much more mature individuals than other mammals. Electrophysiologic characterization of peripheral nerve injury now is feasible in this species.